6533b870fe1ef96bd12cfa23

RESEARCH PRODUCT

Study of eight novel Y-chromosome STRs in a sample from Valencia (East of Spain): analysis of gene and haplotypes frequencies

Maria BrionEduardo MurciaMarina Gisbert GrifoM. Aler

subject

Geneticseducation.field_of_studyPopulationHaplotypeGeneral MedicineY chromosomeValencianlanguage.human_languageGeographyMinisatellitelanguageMicrosatellitePopulation studyeducationGene

description

Because of the great interest in Y-chromosome polymorphisms not only in the forensic field but also in evolutionary studies, the number of described Y-chromosome markers has been increased considerably in the recent literature. During the last few years, new Y-chromosome polymorphisms have been described, including binary polymorphisms, microsatellites and minisatellites. In this study, eight recently described tetranucleotide microsatellites have been analysed: DYS434, DYS437, DYS439, Y-GATA A7.1, Y-GATA A7.2, Y-GATA A.10, Y-GATA C4 and Y-GATA H4. Gene and haplotype frequencies have been estimated in the Valencian population, to determine highly informative haplotypes, using these new Y-STRs combined with the classical ones. D 2003 Elsevier Science B.V. All rights reserved.

https://doi.org/10.1016/s0531-5131(02)00345-x