6533b870fe1ef96bd12cfd57
RESEARCH PRODUCT
Heterocycles from α-aminonitriles.
Till OpatzNicola Ottosubject
NitrileAlkylationCycloaddition ReactionNitrogenOrganic ChemistryIminiumStereoisomerismGeneral ChemistryCarbonCatalysischemistry.chemical_compoundchemistryHeterocyclic CompoundsNitrilesOrganic chemistryMoietyAmine gas treatingReactivity (chemistry)IminesBifunctionalCarbaniondescription
Owing to their various modes of reactivity, α-aminonitriles represent versatile building blocks for the construction of a wide range of nitrogen heterocycles. The present Concept article focuses on synthetic methodologies using their bifunctional nature which is the basis of their reactivity as α-amino carbanions and as iminium ions. Reactions exclusively taking place on either the amine or on the nitrile moiety will not be considered.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-09-12 | Chemistry (Weinheim an der Bergstrasse, Germany) |