6533b870fe1ef96bd12d0497

RESEARCH PRODUCT

Sex Determination by Genomic Dot Blot Hybridization and HLA DQα Typing by PCR from Fixed Tissues

L. PenzesPeter M. SchneiderM. Prager-eberleCh. RittnerL. Pötsch

subject

GROUP-SPECIFIC COMPONENTGenetic variationDot blotComputational biologyTypingFrozen tissueMOLECULAR BIOLOGY METHODSBiologyMolecular biologyParaffin embedded

description

Recent advances in molecular biology methods have significantly increased the ability to detect genetic variation at the genomic level for forensic purposes. However, the quality requirements for blood, fresh or frozen tissue as a source of DNA are a practical limitation for typing the victim in order to conduct investigations on unsolved cases. Since paraffin embedded specimens are easily obtainable the ability to study this material would be of great value in current forensic practice.

https://doi.org/10.1007/978-3-642-77324-2_27