6533b870fe1ef96bd12d070b

RESEARCH PRODUCT

Systemic chemotherapy and pressurized intraperitoneal aerosol chemotherapy (PIPAC): A case report of a multimodal treatment for peritoneal metastases of pancreatic origin

Stefano RotoloCarlo AbatiniAndrea Di GiorgioClaudio LodoliFrediano InzaniFabio PacelliFederica FerracciFrancesco Santullo

subject

Oncologymedicine.medical_specialtymedicine.medical_treatmentCase ReportPancreatic ductal adenocarcinoma03 medical and health sciences0302 clinical medicinePharmacokineticsQuality of lifeInternal medicinemedicineMultimodal treatmentAdverse effectChemotherapyPressurized intraperitoneal aerosol chemotherapy (PIPAC)CarcinomatosisSystemic chemotherapybusiness.industryStandard treatmentfungifood and beveragesPeritoneal metastases030220 oncology & carcinogenesisDrug delivery030211 gastroenterology & hepatologySurgerybusiness

description

Highlights • Integration of PIPAC to systemic chemotherapy can have good tolerance profile. • Repeated biopsies performed during PIPAC allowed therapy-response monitoring. • Analysis of biopsies performed during PIPAC allowed tailoring of chemotherapy. • Integration of PIPAC to systemic chemotherapy can permit good quality of life.

10.1016/j.ijscr.2020.10.054http://europepmc.org/articles/PMC7876684