6533b870fe1ef96bd12d07f8
RESEARCH PRODUCT
The puzzle of metabolic effects of obstructive sleep apnoea in children.
Oreste MarroneMaria R. Bonsignoresubject
Pulmonary and Respiratory Medicinemedicine.medical_specialtymedicine.medical_treatmentPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioCulprit03 medical and health sciences0302 clinical medicineInsulin resistancestomatognathic systemInternal medicineEpidemiologymedicineHumansContinuous positive airway pressureChildTonsillectomySleep Apnea Obstructivebusiness.industryMedicine (all)Metabolic riskmedicine.diseaseSleep in non-human animalsObesitynervous system diseasesrespiratory tract diseasesChild; Humans; Polysomnography; Sleep Apnea Obstructive; Tonsillectomy; Medicine (all); Pulmonary and Respiratory MedicineEndocrinology030228 respiratory systemMetabolic effectsCardiologybusiness030217 neurology & neurosurgeryHumandescription
In adults, obstructive sleep apnoea (OSA) is often associated with metabolic alterations. Although obesity is a major culprit [1], large epidemiological studies have reported a metabolic risk associated with OSA that is independent of obesity. In particular, meta-analyses have shown that effective treatment of OSA by continuous positive airway pressure (CPAP) improves glycaemic control in both diabetic [2] and nondiabetic patients [3]. In obese children with obstructive sleep apnoea insulin resistance is common while lipids do not show a clear pattern
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-04-01 | The European respiratory journal |