6533b871fe1ef96bd12d0f77

RESEARCH PRODUCT

Localization of the bradykinin B2 receptor in uterus, bladder and Madin-Darby canine kidney cells

Ulises NovoaCarlos D. FigueroaWerner Müller-esterlJenny CorthornGloria Valdés

subject

medicine.medical_specialtyTissue FixationReceptor Bradykinin B2Urinary BladderUterusBradykininKidneyRadioligand Assaychemistry.chemical_compoundDogsAntibody SpecificityInternal medicineTumor Cells CulturedmedicineAnimalsHumansTissue DistributionReceptorPharmacologyKidneyParaffin EmbeddingUrinary bladderbiologyurogenital systemReceptors BradykininUterusImmunohistochemistryRadioligand AssayRatsmedicine.anatomical_structureEndocrinologyMicroscopy Fluorescencechemistrybiology.proteinCancer researchAutoradiographyImmunohistochemistryElectrophoresis Polyacrylamide GelFemaleAntibodyCell Division

description

Kinins are biologically active peptides that act through specific receptors, B1 and B2. Here we describe the localization of the bradykinin B2 receptor in Madin-Darby canine kidney cells and in the uterus and urinary bladder of rat or human origin. We discuss the suitability of anti-peptide antibodies to assess the tissue distribution of bradykinin B2 receptors.

https://doi.org/10.1016/s0162-3109(97)00011-8