6533b871fe1ef96bd12d0f89
RESEARCH PRODUCT
The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives
Demetrio RaffaM. Valeria RaimondiFabiana PlesciaGiuseppe DaidoneBenedetta MaggioA. Maria IngarraGianfranco Fontanasubject
Pharmacologychemistry.chemical_compoundElimination reaction4’-substituted spiro [indole-13’-pyrazoles] elimination reactions biaryl derivatives Mechanistic considerationschemistryOrganic ChemistrySubstitution (logic)Reactivity (chemistry)Settore CHIM/06 - Chimica OrganicaIsoindoleSettore CHIM/08 - Chimica FarmaceuticaCombinatorial chemistryAnalytical Chemistrydescription
This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 | HETEROCYCLES |