6533b871fe1ef96bd12d0fc9
RESEARCH PRODUCT
Chronic hyponatremia in a patient with renal salt wasting and without cerebral disease: relationship between RSW, risk of fractures and cognitive impairment
Antonino TuttolomondoVittoriano Della CorteAntonio PintoRosaria Pecorarosubject
0301 basic medicinemedicine.medical_specialtyChronic hyponatremiaNatriuresis03 medical and health sciences0302 clinical medicineCognitionInternal medicineExtracellular fluidCerebral salt wasting syndromeInternal MedicineMedicineHumansWasting SyndromeRenal Insufficiency ChronicAgedbusiness.industryWasting SyndromeRenal salt wasting syndromeSodiumSIADHfood and beveragesnutritional and metabolic diseasesCerebral salt-wasting syndromemedicine.diseaseChronic hyponatremia030104 developmental biologySyndrome of inappropriate antidiuretic hormone secretionEmergency MedicineCardiologyFemaleDifferential diagnosisbusinessHyponatremia030217 neurology & neurosurgeryNatriuretic peptideHumanHyponatremiadescription
Renal salt wasting syndrome (RSW) is defined as a renal loss of sodium leading to hyponatremia and a decrease in extracellular fluid volume (ECV). Differentiation of this disorder from the syndrome of inappropriate antidiuretic hormone secretion (SIADH), a common cause of hyponatremia, can be difficult because both can present with hyponatremia and concentrated urine with natriuresis. Our clinical case about a 78-year-old woman with a recent fracture of the right femur not only confirms that this syndrome can occur in patients without intracranial pathologies (CT documented), but depicts how the hyponatremia caused by RSW can show a chronic, oscillating course. This is an interesting point of view because it suggests to us to consider RSW in the differential diagnosis of patients with chronic hyponatremia.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-08-13 |