6533b871fe1ef96bd12d1021

RESEARCH PRODUCT

Sample pretreatment techniques for oligopeptide analysis from natural sources

Anna PoliwodaPiotr Wieczorek

subject

OligopeptideChromatographysample preparationChemistrySample (material)Chemical fractionationAnalytic Sample Preparation MethodsUltrafiltrationChromatography liquidAnalytic Sample Preparation MethodsChemical FractionationSelective isolationBiochemistryFood AnalysisAnalytical ChemistryAnimalsHumansSample preparationbody fluidsoligopeptidesDialysisFood AnalysisChromatography Liquid

description

The analysis of oligopeptides in samples of food, tissues, and body fluids attracts considerable attention. The complexity of such samples requires efficient sample preparation (i.e., concentration and cleanup) procedures to remove interfering endogenous compounds and inorganic or organic salts. The methods of sample pretreatment that enable effective and selective isolation and/or preconcentration of oligopeptides from complex sample matrices have been reviewed. In each case, examples of application were presented and discussed, taking into account selectivity, enrichment, method automation, cleanup, and environmental aspects of the developed methods.

https://doi.org/10.1007/s00216-008-2345-9