6533b871fe1ef96bd12d10ce

RESEARCH PRODUCT

Heart failure and chronic kidney disease in a registry of internal medicine wards

Rosa Di CostanzoRoberto CorinaldesiFederica QuagliaUmberto Vespasiani GentilucciGiancarlo AgnelliM. VanoliRoberta ForlanoValeria SavojardoLuca BertoneElisa FabbriAntonino Di PinoClaudia AmoliniGiampiera BertolinoPaolo Cavallo PerinPaola BonaraTommaso BarniniFabrizio FabrisPaola Di CoratoMaria Rosaria BarbellaFrancesco FranceschiElisabetta BergamiRoberto ManfrediniSonia SeghezziEnrico StrocchiMaria Domenica CappelliniAntonio ManucraAlberto TedeschiMaurizio CorsiGabriella GrudenGiuseppe LicataMarianna ZardoEmanuela MarchesiniLuca PasinaMaria Ester ModeoMosè BartoneBarbara NardoUmberto GualtieriSabbatini MartaCaterina CenciAlessia CoralliGiorgio AnnoniLucrezia De FeudisV. MontiPietro SerraAnna Maria StanzialAntonio BonelliGianpaolo ReboldiFrancesco PaciulloFerdinando MassariGraziana LupattelliGiorgio SestiSilvia FargionAngela SciacquaGiovanna FabioSilvia Di CarloMaria Grazia SerraEmanuele Durante-mangoniCorrao SalvatoreMaria Angela BecchiMargherita Migone De AmicisFrancesco GulloSilvia CappelliFlora PeyvandiPaolo GalloChiara MazzarelliDaniela CalipariFerdinando Carlo SassoCarlo CagnoniLaura CarassaleDonatella RennaPaola LoriaDavide GhelfiAlessandra QuercioliMaria Teresa GuagnanoLuana CastoldiMassimo DelfinoCosimo MorabitoGiuseppe MuscaFrancesca TurattoSilvia ProloLina FalangaMichela ZanettiAntonio PerciccanteFrancesco PurrelloMarco CicardiMaria Beatrice SecchiMauro TettamantiMaria Rosaria RizzoLuigi AnastasioC. MasalaAndrea Maria MarescaElena SilvestriDomenico PriscoFilippo PedrazzoliMarco BertolottiGuido De MarcoGiancarlo TraisciMaria Carmela CarboneFilippo Rossi FanelliMaria ValentiIlenia PepeDeborah MelisChristian BraccoGiorgio ManiscalcoAntonella GalloDaniela D'angeloAlfonso IorioGianfranco MartucciTatiana TonellaIlaria SerioWu Sheng ChinMichela QuaglioloCordischi ChiaraAndrea SaccoPietro TizzaniAntonio MammarellaDonatella SettiDamiano RizzoniLucia GottardoOlga CuccurulloGino Roberto CorazzaRinaldo StriuliElmo MannarinoGuido MoreoLuana CastiglioniG. VaudoTeresa SalvatoreMaurizio BicchiRaffaella RossioFrancesco VioliDonatella MagalottiGiuseppe ZuccalàLuca PuccettiLuigi FenoglioDaniela TirottaAlessandra FiorentiniOliviero OlivieriChristian FolliAlberto BurattiFrancesco Saverio VellaVincenzo FontanaGiulia GrignaniLaura GasbarroneSara ZazzettaAntonio BrucatoMarco ZoliMichele CortellaroStella ProviniClaudio BorghiMario BarbagalloRodolfo TassaraSara ContiniElisa Rebecca RinaldiLidia PlancesStefano VolpatoAlessandra BarrecaLudovica PerriStefania AlborghettiChiara Valentina LuglioDonatella PadulaCodjo Djignefa DjadeMaria Rachele MeroniMara BulgheroniGiuseppe Riccardo CentenaroChiara BagnatoSalvatore PiroNicola Lucio LiberatoLuigi BolondiFranco RicciAnnalisa SpallutiLuciano OttonelloGiordano BernasconiAntonio PicardiMichela CarlonRiccardo UtiliMaria Alice FerriRoberto ValentiFrancesca VeltriGiorgio MenardoGiuliana MicaleMaria Cristina BaroniPiergiorgio GaudenziPallante RaffaeleSimona SestiliGiuseppe RomanelliRoberto De GiorgioL. RascitiFranco ArturiMarta BovioAlessandro SquizzatoLeonella PasqualiniPier Leopoldo CapecchiAlfredo PostiglioneMaura MarcucciAntonio AmorosoSarah DamantiLucia SofiaE MannarinoFrancesca PeregoSilvia CaporotundoGiuseppe DelitalaGaetano ServiddioBarbara FerrariLorenzo Mauro CarozzaRaffaella SalmiGiacomo FeraPier Mannuccio MannucciDaniela MariPasquale MansuetoCarlotta FranchiSilvia Li BassiLuca SantiMichele QueroGraziella BrunoElsa SferrazzoMartino BellusciSebastiana AtzoriMauro MaurantonioMauro BernardiMaria Sole LilleriMaria Loreta Di LucaCarlo SabbàLuigi CriccoMancuso GAlessia Valentina GiraudoGiovanni Battista BianchiValentina GrassoChiara MussiGiovanni MurialdoChiara BrignoneMarco PalaMarina MagentaFranco DallegriGiuseppe MontrucchioPamela RondelliCarlo L. BalduiniP. M. MannucciGiampiero BenettiFabio FabbianMassimo GunelliFabio PignattiEmanuela MiceliTiziana TogninStefania PuglieseFranco Laghi PasiniFrancesco SalernoMarengoni AlessandraRosa ScipioniA. NobiliMaria Antonietta BleveGianluca CasellaFrancesca MedaElisabetta GrecoAntonio Gidaro Marina MagentaFabio MagriniElena SuccurroEmanuela RizzioliValeria RaparelliSusanna GamberiniCaterina PiraliLigia J. DominguezStefania BasiliMatteo PirroLuigi CalvoBartolomeo LorenzatiRanuccio NutiFrancesco PerticoneClaudio FerriGiovanbattista RiniChristian MolinoStefano CartaMarta MolaroFrancesco De StefanoMaria Teresa LaietaAnnamaria AquilinoSabrina Giaquinto OspedaleGaetano DentamaroMartina RuvioRaffaele LandolfiRenzo RozziniMauro SerraGiovanni DavìCarlo SelmiRenato FellinG. LupattelliSilvia GhidoniMarco Vincenzo LentiAlberto AuteriAlessandro GiordanoEleonora SparacioMarco FalconeRoberto FavaAnna Laura PasquiGiuseppe PalascianoDaniela Di PintoGianfranco GuarnieriRosa LombardiF. PaciulloLuigina GuastiSioulis FotiniMaria MagniniMauro PoddaAlessandro MarsegliaSilvia AccordinoEnrico Agabiti RoseiCaterina CapobiancoAlessio ConcaGiuseppe PaolissoLara RebellaAlessandra FantuzziPaolo RossiAndrea SempliciniGianluigi VendemialeLuisa RoncariAntonio GriecoRoberto ScottoNobili AlessandroValter MonzaniEugenio RuggeriStefania Bottone

subject

medicine.medical_specialtyChronic kidney disease; Elderly; Heart failure; REPOSI; Gerontology; Geriatrics and GerontologyHeart failure; Elderly; Chronic kidney disease; REPOSIChronic kidney disease; Elderly; Heart failure; REPOSI; Humans; Sleep Apnea Syndromes; Noninvasive Ventilation; Gerontology; Geriatrics and GerontologyChronic kidney disease; Elderly; Heart failure; REPOSIRenal functionHeart failure; chronic kidney disease; elderly; registry; REPOSIHeart failureregistryTertiary careSleep Apnea SyndromeElderlySleep Apnea SyndromesInternal medicineChronic kidney diseaseEpidemiologymedicineHumansNoninvasive Ventilationbusiness.industryREPOSIChronic kidney disease; Elderly; Heart failure; REPOSI; Humans; Sleep Apnea Syndromes; Noninvasive Ventilation; Geriatrics and Gerontology; Gerontologymedicine.diseaseHeart failureHeart failure Elderly Chronic kidney disease REPOSIIcd codesGeriatrics and GerontologybusinessClinical recordBody mass indexGerontologyKidney diseaseHuman

description

Background: The aim of the present study was to evaluate the association between heart failure (HF) and chronic kidney disease (CKD) in tertiary care centers using the clinical records of patients enrolled in internal medicine departments.Patients and methods: We used the clinical records of 1380 elderly patients to identify patients with a history of HF and CKD using admission ICD codes and glomerular filtration rate (GFR) formulas. Magnitude and strength of such associations were investigated by univariable and multivariable analysis.Results: Of the 1380 patients enrolled, 27.9% had HF (age 80 ± 7, BMI 27 ± 6 kg/m2) and 17.4% CKD (age 81 ± 7, BMI 26.8 ± 6 kg/m2). Both groups were significantly older (P <' 0.0001) with BMI higher than the patients without those diagnosis (P < 0.02). Patients with a history of CKD showed higher non-fasting glycaemia (140 ± 86 vs. 125 ± 63 mg/dL, P < 0.001). CKD was significantly associated with HF (P < 0.0001). Patients with HF had an estimated GFR lower than patients without HF (P < 0.0001). Comorbidity and severity indices were significantly higher in subjects with HF (P < 0.0001) and CKD (P < 0.0001) than in those without. Multivariable analysis showed a significant association between HF and age (for five years increase OR 1.13, P < 0.009), BMI (for each 3 kg/m2 increase OR 1.15, P < 0.001), GFR (for each decrease of 10 mL/min increase OR 0.92, P < 0.002) and severity index (IS) (for each 0.25 units increase OR 1.43, P < 0.001).Conclusion: HF on admission is strongly associated with CKD, older age, BMI, and SI. These data focus the value of epidemiological studies such REPOSI in identifying and monitoring multimorbidity in elderly.

10.1016/j.eurger.2014.08.005https://hdl.handle.net/11380/1207213