6533b871fe1ef96bd12d1944

RESEARCH PRODUCT

Normal Values of Oxygen Concentration in Human Blood

Rolf ZanderFriedrich Mertzlufft

subject

medicine.medical_specialtyOxygen supplyHuman bloodChemistryHypoxia (environmental)Normal valuesPartial pressurerespiratory tract diseasesHypoxemiaInternal medicinemedicineCardiologyLimiting oxygen concentrationmedicine.symptomPerfusioncirculatory and respiratory physiology

description

Under physiological conditions, the oxygen supply as the product of O2-concentration (mlO2/dl; %(v/v)) and perfusion is influenced by many factors (cf. Fig. 1): perfusion on one hand, oxygen partial pressure (pO2; mmHg), haemoglobin (Hb) concentration (g/dl) and O2 binding power of Hb on the other hand. Under pathological conditions, oxygen supply disturbances are related to hypoxemia, i.e. reduction of O2-concentration in the blood. The differential diagnosis of hypoxemia includes normoxic, hypoxic and circulatoric disturbances of oxygen supply (cf. Fig. 1). Thus it is necessary to describe a NORMOXIC HYPOXEMIA (anemic or toxemic), a HYPOXIC HYPOXEMIA (decreased O2-concentration caused by a reducted pO2) and an ISCHEMIC HYPOXEMIA (reduction of perfusion). In clinical medicine, O2 supply disturbances are commonly judged by measurement of the pO2. However, hypoxemia (reduction of O2-concentration) is only in part characterized by hypoxia (decrease of pO2). Furthermore the pO2, however, compared to the oxygen concentration is characterized by a tremendous intra- and interindividual range of variation(1,2,3).

yearjournalcountryeditionlanguage
1984-01-01
https://doi.org/10.1007/978-1-4684-4895-5_56