6533b871fe1ef96bd12d1c28

RESEARCH PRODUCT

Re: ?Splenic marginal zone B-cell lymphoma associated with primary Sj�gren?s syndrome?

Vito FrancoEmilio IannittoClaudio TripodoAda Maria FlorenaS. NishiyamaS. Miyawaki

subject

Pathologymedicine.medical_specialtymedicine.medical_treatmentSplenectomyImmunologyCryoglobulinRheumatologyMedicineHumansB cellAgedbusiness.industrySplenic NeoplasmsLymphoma B-Cell Marginal ZoneGeneral MedicineSwollen lymph nodesmedicine.diseaseMarginal zoneCryoglobulinemiaLymphomaSplenic Neoplasmmedicine.anatomical_structureLymphatic systemSjogren's SyndromeFemalemedicine.symptombusinessHuman

description

We describe a 67-year-old woman with primary Sjögren's syndrome who developed a splenic marginal zone B-cell lymphoma, and complained of a dry mouth and Raynaud's phenomenon. She had splenomegaly, swollen lymph nodes and monoclonal IgM-kappa cryoglobulin. After splenectomy, Raynaud's phenomenon had improved with the decrease of cryoglobulin. This is the first case of primary Sjögren's syndrome with splenic marginal zone B-cell lymphoma to be reported.

yearjournalcountryeditionlanguage
2003-07-04Clinical Rheumatology
https://doi.org/10.1007/s10067-004-0993-5