6533b871fe1ef96bd12d2572

RESEARCH PRODUCT

Sesquiterpenes from Onopordum illyricum and their antifeedant activity

Maurizio BrunoSergio RosselliAntonella MaggioMarisa CanzoneriMonique S. J. Simmonds

subject

PharmacologybiologyTraditional medicineSesquiterpenes Onopordum illyricun antifeedant activityOnopordumPlant ScienceGeneral MedicineFeeding BehaviorSettore CHIM/06 - Chimica OrganicaAsteraceaeSpodopterabiology.organism_classificationComplementary and alternative medicinePhytochemicalLarvaDrug DiscoveryAnimalsSettore BIO/15 - Biologia FarmaceuticaSpodoptera littoralisSesquiterpenesOnopordum illyricum

description

Phytochemical investigation of the acetone extract of the aerial parts of Onopordum illyricum L. afforded five known sesquiterpenoids: compounds 3 and 4 already isolated from O. illirycum, and 8α-[4′-hydroxymethacryloyloxy]-sonchucarpolide (1), 8α-[4′-hydroxymethacryloyloxy]-4-epi-sonchucarpolide (2) and 8-(4′-hydroxymethacryloyl)-dehydromelitensin (5), not previously detected in this species. Compounds 4 and 5 showed moderate antifeedant activity against larvae of Spodoptera littoralis.

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