6533b871fe1ef96bd12d2573

RESEARCH PRODUCT

Post-Infectious Myocardial Infarction: New Insights for Improved Screening

Marianne ZellerPatrick ManckoundiaAlain PutotYves CottinFrédéric Chagué

subject

Acute coronary syndromemedicine.medical_specialtylcsh:Medicine030204 cardiovascular system & hematologyType 2 myocardial infarctionelderlyArticleacute coronary syndromeSepsisPathogenesissepsis03 medical and health sciences0302 clinical medicineInternal medicinemedicinepneumonia030212 general & internal medicineMyocardial infarctionbusiness.industryIncidence (epidemiology)lcsh:Rpulmonary tract infectionGeneral MedicineOdds ratiomedicine.diseaseConfidence intervalinfectionPneumoniabusinessin-hospital mortality

description

Acute infection is suspected of involvement in the onset of acute myocardial infarction (MI). We aimed to assess the incidence, pathogenesis and prognosis of post-infectious MI. All consecutive patients hospitalized for an acute MI in coronary care units were prospectively included. Post-infectious MI was defined by a concurrent diagnosis of acute infection at admission. Type 1 MI (acute plaque disruption) or Type 2 MI (imbalance in oxygen supply/demand) were adjudicated according to the universal definition of MI. From the 4573 patients admitted for acute MI, 466 (10%) had a concurrent acute infection (median age 78 (66–85) y, 60% male), of whom 313 (67%) had a respiratory tract infection. Type 2 MI was identified in 72% of post-infectious MI. Compared with other MI, post-infectious MI had a worse in-hospital outcome (11 vs. 6% mortality, p &lt

yearjournalcountryeditionlanguage
2019-06-11Journal of Clinical Medicine
10.3390/jcm8060827http://dx.doi.org/10.3390/jcm8060827