6533b871fe1ef96bd12d2597

RESEARCH PRODUCT

Temporal control of xyloglucan self-assembly into layered structures by radiation-induced degradation

Maria Antonietta SabatinoClelia DispenzaDonatella BuloneMaria Laura Di GiacintoSimona TodaroMaria Rosalia MangionePasquale Picone

subject

Materials Chemistry2506 Metals and AlloysTime FactorsMaterials scienceMorphology (linguistics)Polymers and PlasticsCell Survival02 engineering and technologyengineering.material010402 general chemistry01 natural sciencesPolymerizationNeuroblastomachemistry.chemical_compoundBiopolymersDynamic light scatteringCell Line TumorMaterials TestingSpectroscopy Fourier Transform InfraredMaterials ChemistryHumansHigh energy-irradiationComposite materialFourier transform infrared spectroscopyXyloglucanGlucansPolymers and PlasticViscosityMedicine (all)Organic ChemistryTemperatureHydrogelsSelf-assembly021001 nanoscience & nanotechnology0104 chemical sciencesXyloglucanHydrogelMembranechemistryChemical engineeringGamma RaysSelf-healing hydrogelsengineeringXylansThermoresponsive biopolymerBiopolymerSelf-assemblyShear Strength0210 nano-technology

description

Partially degalactosylated xyloglucan from tamarind seeds (Deg-XG) is a very appealing biopolymer for the production of in situ gelling systems at physiological temperature. In this work, we observe that the morphology of hydrogels evolves towards high degrees of structural organization with time, yielding to dense stacks of thin membranes within 24 h of incubation at 37 °C. We also explore the possibility offered by gamma irradiation of controlling the time scale of this phenomenon, the final morphology and mechanical properties of the system. Structural and molecular modifications of Deg-XG with dose are investigated by FTIR, dynamic light scattering (DLS) and rotational viscosimetry. The impact on gelation ability and gel strength is studied by rheological analysis. The morphology evolution is investigated by SEM analysis, and absence of cytotoxicity verified by MTS assay and optical microscopy of neuroblastoma cells.

yearjournalcountryeditionlanguage
2016-01-01Carbohydrate Polymers
https://doi.org/10.1016/j.carbpol.2016.07.005