6533b871fe1ef96bd12d2645

RESEARCH PRODUCT

[3+2]‐Cycloadditions of N ‐Cyano Sulfoximines with 1,3‐Dipoles

Felix KrauskopfKari RissanenCarsten BolmKhai-nghi Truong

subject

betaiinisulfoximinebioaktiiviset yhdisteetOrganic ChemistryTriazoleOxadiazoleCycloadditiontriazolechemistry.chemical_compoundDipolechemistryPolymer chemistrybetaine13-dipolePhysical and Theoretical Chemistry13-dipolecycloadditionoxadiazoleorgaaniset yhdisteet

description

Involving the cyano group of N‐cyano sulfoximines in [3+2]‐cycloaddition reactions with 1,3‐dipoles provides practical routes for the construction of 5‐membered heterocycles bearing sulfoximinoyl moieties. An ytterbium‐catalyzed cycloaddition utilizing hydrazonoyl chlorides was developed, as well as a reaction involving imidoyl chlorides proceeding without the aid of a catalyst. Following these protocols, a range of sulfoximines with N‐1,2,4‐triazolyl and N‐1,2,4‐oxadiazolyl substituents was prepared. peerReviewed

yearjournalcountryeditionlanguage
2020-04-20European Journal of Organic Chemistry
https://doi.org/10.1002/ejoc.202000335