6533b872fe1ef96bd12d2c70

RESEARCH PRODUCT

Evaluation of Treatment Integrity: The Treatment Specificity Index

Visar RudariChristine SchimmingMartin HautzingerFlorian WeckFlorian GrikscheitUlrich StangierMaria WeigelThomas Heidenreich

subject

Oncologymedicine.medical_specialtyIndex (economics)business.industryPsychological interventionRelapse preventionlaw.inventionClinical PsychologyArts and Humanities (miscellaneous)Randomized controlled triallawInternal medicinemedicinePhysical therapyInternal validitybusiness

description

Objective To differentiate between treatments in a randomized controlled trial (RCT), therapies need to display not only high purity but also high specificity. The aim of this study was to demonstrate the benefits of calculating a treatment specificity index for the evaluation of treatment differentiation. Method Based on an RCT of relapse prevention in depression, comparing a cognitive with a psychoeducational treatment, the specificity and the purity index were calculated. Results As indicated by the specificity index, both conditions differed in their levels of implemented specific and common interventions. A significant relationship was found between symptom change before a therapy session and treatment specificity. Conclusions The specificity index is an appropriate method for enhancing the internal validity of RCTs in evaluating treatment integrity.

https://doi.org/10.1002/jclp.22172