6533b872fe1ef96bd12d2c9d

RESEARCH PRODUCT

1H-NMR studies on poly(oxyethylene)-bound oligopeptides

Murray GoodmanManfred MutterRobert P. SaltmanAnthony A. RibeiroKarsten Bode

subject

BiomaterialsOligopeptideChemistryOrganic ChemistryBiophysicsProton NMROrganic chemistrymacromolecular substancesGeneral MedicineSpectroscopyBiochemistryProtein secondary structure

description

Conformational studies on poly(oxyethylene)-bound homo-, oligo-, guest-host, and sequential peptides synthesized according to the liquid-phase method were carried out by means of 1H-nmr spectroscopy. The solubilizing effect of the C-terminal polymeric support allowed a thorough investigation of the secondary structure in solution.

https://doi.org/10.1002/bip.360220126