6533b872fe1ef96bd12d2d21

RESEARCH PRODUCT

Hippocampal Sharp Waves: A Physiological Correlate of LTP?

Helmut L. HaasGyörgy Buzsáki

subject

education.field_of_studynervous systemChemistrymusculoskeletal neural and ocular physiologyPopulationGranule (cell biology)Long-term potentiationPopulation spikeHippocampal formationeducationNeuroscienceSharp wave

description

The irregularly occurring large amplitude hippocampal sharp waves (SPWs) are correlated with synchronous population bursts of CA1-CA3 and subicular pyramidal cells, dentate granule cells and interneurons in all hippocampal fields. We suggest that the SPW-associated neuronal burst is the best candidate for a physiological basis of long-term potentiation (LTP).

https://doi.org/10.1007/978-3-642-73202-7_26