6533b872fe1ef96bd12d3883

RESEARCH PRODUCT

Additional file 1 of Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure

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Additional file 1: eTable 1. Esophageal and nasal pressure swings according to acute respiratory failure etiology. Data are presented as median and interquartile ranges (IQR). eFigure 1. Pearson���s R showing correlations between ��Pes and ��Pnos at 24 hours after splitting the study population according to the NRS received. eFigure 2. Bland-Altman analysis assessing the agreement between ��Pes measured with esophageal manometry and estimated based on ��Pnos (��Pes, estimated) and computed as k����Pnos, where k is the average ratio of ��Pes to ��Pnos measured at baseline. At T2 Bland-Altman methods showed a bias of 0.1 cmH2O and 95% limits of agreement, LoA, from ���2.0 to 2.1 cmH2O (95.1% of measurements within LoA). Among patients receiving HFNC bias was 0.1 cmH2O and 95% LoA were from ���2.1 to 2.3 cmH2O, while in patients receiving NIV bias was 0.0 and 95% LoA from ���2.0 to 2.0 cmH2O. eTable 2. General and clinical characteristics of the study population according to respiratory support at day 3. Data are presented as number (n) and percentage for dichotomous values or median and interquartile ranges (IQR) for continuous values.