6533b872fe1ef96bd12d38a9
RESEARCH PRODUCT
Molecular relationship among Salmonella dublin isolates identified at the Center for Enterobacteriaceae of Palermo during the years 1971-85.
A. NastasiD. OlivaScarlata GCaterina MamminaMassenti MfVillafrate Mrsubject
DNA BacterialSalmonellaEpidemiologyVirulenceChloramphenicol ResistanceBiologymedicine.disease_causeMicrobiologyDisease OutbreaksMicePlasmidAntibiotic resistanceAmp resistanceSalmonellamedicineAnimalsHumansChildMice Inbred BALB CSalmonella Infections AnimalMolecular epidemiologyVirulenceTetracycline ResistanceOutbreakDrug Resistance MicrobialVirologyGastroenteritisInfectious DiseasesItalyStreptomycinMetalsSalmonella InfectionsStreptomycinCattleFemaleAmpicillin Resistancemedicine.drugPlasmidsResearch Articledescription
SUMMARYA molecular epidemiological study was carried out on 60Salmonella dublinisolates identified at the Southern Italy Enterobacteriaceae Center between 1971 and 1985. These included 23 isolates from children with diarrhoea in Palermo obtained during 1984.All isolates from the outbreak of gastroenteritis in children were resistant to chloramphenicol and streptomycin and harboured two plasmids of 50 MDa and 3 MDa molecular weight, whereas the majority of the isolates identified before 1984 were susceptible to these antibiotics and carried only a 50 MDa molecular weight plasmid. FourS. dublinstrains successively identified from cattle (Palermo, Foggia, Portici) and from a child (Palermo) were shown to possess similar antibiotic resistance patterns and plasmid profiles toS. dublinisolates from the outbreak of gastroenteritis in children.The 50 MDa plasmid was shown to be associated with virulence in mice, while it was not possible to assign any genetic function to the 3 MDa plasmid.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-10-01 | Epidemiology and infection |