6533b872fe1ef96bd12d38f1

RESEARCH PRODUCT

Spectrophotometric determination of adrenaline with an oxidative column in a FIA assembly

J. Martínez CalatayudAnatol Kojło

subject

ChromatographyAqueous solutionChromatographyEpinephrinemedicine.diagnostic_testCalibration curveClinical BiochemistryPharmaceutical Sciencechemistry.chemical_elementManganesePharmaceutical formulationAnalytical ChemistrychemistrySpectrophotometryDrug DiscoverymedicineIndicators and ReagentsSpectrophotometry UltravioletOxidation-ReductionSpectroscopy

description

Abstract A single channel FIA assembly is proposed for the spectrophotometric determination of adrenaline, the aqueous sample solution is directly injected into the carrier stream leading the sample through a manganese dioxide column at 80°C, and on to the spectrophotometer flow-cell. The calibration graph is linear up to 17 ppm of adrenaline. The influence of other substances has been studied and the method has been applied to the determination of adrenaline in a pharmaceutical formulation.

yearjournalcountryeditionlanguage
1990-01-01Journal of Pharmaceutical and Biomedical Analysis
https://doi.org/10.1016/0731-7085(90)80098-a