6533b872fe1ef96bd12d3a28

RESEARCH PRODUCT

A comparative study of the application of the method of least-squares in the potentiometric determination of protonation constants.

M.celia GarciaC. MongayG. Ramis

subject

ChemistryComputational chemistryPotentiometric titrationLinear regressionAnalytical chemistryProtonationDiprotic acidOrder of magnitudeAnalytical Chemistry

description

Methods of simple and multiple linear regression applied to the potentiometric determination of protonation constants of diprotic and triprotic acids are studied critically. The best way of fitting the data, according to the order of magnitude of the constants, is established. The conclusions are checked by calculating the protonation constants of succinic and citric acids.

10.1016/0039-9140(82)80185-9https://pubmed.ncbi.nlm.nih.gov/18963156