6533b872fe1ef96bd12d40e5

RESEARCH PRODUCT

Glycosylation-induced asymmetric synthesis: β-amino acid esters via Mannich reactions

Petra AllefHorst Kunz

subject

Inorganic Chemistrychemistry.chemical_classificationchemistry.chemical_compoundGlycosylationStereochemistryChemistryOrganic ChemistryEnantioselective synthesisKeteneOrganic chemistryPhysical and Theoretical ChemistryCatalysisAmino acid

description

Abstract Activation of Schiff bases by N-glycosylation induces asymmetric Mannich reactions with O-silyl ketene acetals to give β-amino acid esters in good yields.

https://doi.org/10.1016/s0957-4166(99)00541-8