6533b872fe1ef96bd12d4392
RESEARCH PRODUCT
"Synaptic" ribbons and spherules of the rat pineal gland: day/night changes in vitro?
M. KarasekL. Vollrathsubject
Malemedicine.medical_specialtyGeneral NeuroscienceSynaptic MembranesRats Inbred StrainsBiologyOrgan culturePineal GlandIn vitroCircadian RhythmRatsRat Pineal GlandPineal glandMicroscopy Electronmedicine.anatomical_structureEndocrinologynervous systemIn vivoInternal medicineSynapsesmedicineAnimalssense organsSynaptic Vesiclesdescription
In the present study pineal glands of rats aged 69–71 days were studied in vivo and in vitro with respect to day/night changes of “synaptic” ribbons and spherules. It was found that ribbons outnumber spherules by a factor of 3. In vivo, both ribbons and spherules show a roughly 3-fold increase in number at 1 a.m. when compared to 1 p.m. Up to 39 h in vitro, the two structures in question did not reveal day/night differences in amount, suggesting that diurnal rhythmicity of the gland did apparently not persist in organ culture. After 3 h in organ culture, the spherules, but not the ribbons, showed a striking increase in number, showing that ribbons and spherules may be governed by different mechanisms.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1982-05-01 | Experimental brain research |