6533b873fe1ef96bd12d4c7b

RESEARCH PRODUCT

Proliferative verrucous leukoplakia, squamous cell carcinoma and axillary metastasis.

Márcio Ajudarte LopesAdriana Elisa Brasil MoreiraRodrigo Ribas Dias Dos ReisOslei Paes De AlmeidaAdriele Ferreira Gouvêa

subject

Pathologymedicine.medical_specialtyCellAxillary MetastasisMalignant transformationNeoplasms Multiple PrimaryOral and maxillofacial pathologyCarcinomamedicineHumansBasal cellGeneral DentistryLeukoplakiabusiness.industryMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Axillastomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyLymphatic MetastasisUNESCO::CIENCIAS MÉDICASAxillaCarcinoma Squamous CellSurgeryFemaleMouth NeoplasmsLeukoplakia Oralbusiness

description

Proliferative verrucous leukoplakia (PVL) is an aggressive form of oral leukoplakia with multifocal presentation, high rates of recurrence and malignant transformation. Although development of regional lymph node metastasis is relatively frequent in patients with oral squamous cell carcinoma, axillary metastasis is quite uncommon. This paper presents a case of a 64-year-old female patient who was diagnosed with PVL and developed five oral squamous cell carcinomas and later an axillary lymph node metastasis.

https://pubmed.ncbi.nlm.nih.gov/20173705