6533b873fe1ef96bd12d4c7c

RESEARCH PRODUCT

Effect of Rotary Instrument Mineral Oil Lubricant on Osseointegration: A Randomized, Blinded Study in Rabbits

Carmen Carda-batallaArturo Sánchez-pérezFrancisco Javier Sarobe-oyarzunScott DavisJosé Javier Martín-de-llanoAna Belén Cano-tovar

subject

medicine.medical_treatmentDentistryOsseointegrationRandom Allocation03 medical and health sciences0302 clinical medicineImplants ExperimentalOsseointegrationmedicineAnimalsMineral OilBone formationLubricantDental implantMineral oilLubricants030304 developmental biologyDental ImplantsTitanium0303 health sciencesTibiabusiness.industryDental Implantation Endosseous030206 dentistryRabbitsOral Surgerybusinessmedicine.drugBlinded study

description

The mechanisms of early failures in dental implant osseointegration are unclear. A possible cause of low levels of bone formation is lubricant contamination on implants during insertion. To explore the impact of lubricant contamination on dental implants, we used 5 New Zealand rabbits and inserted 2 implants per tibia in each animal for a total of 4 implants per animal (20 implants in total). In general, bicorticalization was achieved. The first implant was placed as suggested by the manufacturer with no lubricant used (control). The second implant was placed using a freshly lubricated contra-angle handpiece, which was used only for the test implants. Implant allocation was randomized, and the examining histologist was blinded to the results. All implants were placed by the same surgeon. The animals were maintained in accordance with animal experimentation guidelines. None of the implants failed to osseointegrate. Moreover, no significant difference was observed between the test and control groups. Based on the results of this study, the use of rotary instrument mineral oil lubricant did not jeopardize the osseointegration of dental implants in New Zealand rabbits.

https://doi.org/10.1563/aaid-joi-d-18-00080