6533b873fe1ef96bd12d4d4f

RESEARCH PRODUCT

Ipsilesional and contralesional regions participate in the improvement of poststroke aphasia: a transcranial direct current stimulation study

Serena IndovinoVanessa CostaFilippo BrighinaGiuseppe GigliaBrigida Fierro

subject

medicine.medical_specialtyHemispheric strokemedicine.medical_treatmentlanguage recoveryStimulationTranscranial Direct Current StimulationFunctional LateralityElectrode polarityPhysical medicine and rehabilitationArts and Humanities (miscellaneous)AphasiaAphasiamedicineHumanslanguage networkStrokeCerebral CortexTranscranial direct-current stimulationMedicine (all)Middle Agedmedicine.diseaseStrokeCrossed aphasiaTreatment OutcomeFemaleNeurology (clinical)medicine.symptomPsychologyNeurosciencePsychomotor PerformancePicture namingHuman

description

In the past few years, noninvasive cerebral stimulations have been used to modulate language task performance in healthy and aphasic patients. In this study, a dual transcranial direct current stimulation (tDCS) on anterior and posterior language areas was applied for 2 weeks to a patient with a possible crossed aphasia following a right hemisphere stroke. Inhibitory cathodal stimulation of the right Brodmann areas (BA) 44/45 and simultaneous anodal stimulation of the left BA 44/45 improved the patient’s performance in picture naming. Conversely, the same bilateral montage on BA 39/40 did not produce any significant improvement; finally, electrode polarity inversion over BA 39/40 yielded a further improvement compared with the first anterior stimulation. Our findings suggest that ipsilesional and contralesional areas could be useful in poststroke functional reorganization and provide new evidences for the therapeutic value of tDCS in aphasia.

yearjournalcountryeditionlanguage
2015-04-01Neurocase
https://doi.org/10.1080/13554794.2014.927508