6533b873fe1ef96bd12d4dc4

RESEARCH PRODUCT

New Obesity Indices and Adipokines in Normotensive Patients and Patients With Hypertension

Maciej BanachMariusz StępieńJacek RyszMarek ParadowskiAnna StępieńRafał Nikodem WlazełRizzo ManfrediPeter P. Toth

subject

AdultLeptinMalemedicine.medical_specialtyAdipokinePilot ProjectsIntra-Abdominal FatBody adiposity indexBody Mass IndexWaist–hip ratioPredictive Value of TestsInternal medicineobesity hypertension adipokines obesity indicesHumansMedicineResistinObesityAdiposityAdiponectinWaist-Hip Ratiobusiness.industryLeptinnutritional and metabolic diseasesMiddle Agedmedicine.diseaseObesityEndocrinologyCase-Control StudiesHypertensionFemaleResistinAdiponectinWaist CircumferenceCardiology and Cardiovascular MedicinebusinessBody mass indexBiomarkershormones hormone substitutes and hormone antagonists

description

We compared the obesity parameters and selected adipokines—leptin, adiponectin, and resistin—in obese patients with hypertension and normotensive patients. A total of 67 nondiabetic obese outpatients were divided into 2 groups: A–hypertensive and B–normotensive. Serum levels of leptin, adiponectin, resistin, and insulin were measured. Weight, height, waist circumference, and hip circumference were measured to calculate waist-to-hip ratio (WHR), weight-to-height ratio, visceral adiposity index, and body adiposity index (BAI). Among patients with hypertension, significant positive correlations were observed between leptin and body mass index and BAI ( r = .31 and r = .63, respectively). In normotensive patients, leptin positively correlated with BAI ( r = .73, P < .01) and negatively with WHR ( r = −.55, P < .0001); adiponectin negatively correlated with WHR ( r = .38, P < .01) and BAI ( r = .52; P < .0001), and resistin negatively correlated with WHR ( r = −.36, P < .05). In conclusion, visceral obesity and leptin are associated with hypertension in obese patients.

yearjournalcountryeditionlanguage
2013-05-03Angiology
https://doi.org/10.1177/0003319713485807