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RESEARCH PRODUCT
Is laparoscopic approach still a risk factor for postappendectomy intra-abdominal abscess?
Joaquín Ortega SerranoCarlos León EspinozaLeticia Pérez SantiagoMaría Carmen Fernández-morenoRosa Martí Fernándezsubject
AdultMalemedicine.medical_specialtyAbdominal AbscessCritical Care and Intensive Care MedicineYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsAppendectomyHumansMedicineRisk factorAbscessRetrospective StudiesPostoperative Carebusiness.industryIncidence (epidemiology)030208 emergency & critical care medicineRetrospective cohort studyPerioperativeMiddle AgedAppendicitismedicine.diseaseAppendicitisSurgeryLogistic ModelsPropensity score matchingCohortFemaleLaparoscopySurgerybusinessdescription
Background The impact of laparoscopic appendectomy (LA) on the incidence of intra-abdominal abscess (IAA) remains controversial. We aimed to identify risk factors for postappendectomy IAA and assess the impact of appendectomy approach in postoperative morbidity. Methods A retrospective single-center study including consecutive patients who underwent appendectomy for acute appendicitis between 2015 and 2018 was performed. Demographic, clinical, intraoperative, and perioperative variables were collected. Univariate and multivariate analyses was performed to detect independent risk factors for IAA. Comparison of LA and open appendectomy was conducted, and propensity score model (PSM) was used to overcome differences between groups. Independent risk factors for IAA were identified by univariate and multivariate analyses in the PSM cohort. Results A total of 532 appendectomies were included. The median age was 35 years. Three hundred two patients (56.7%) underwent LA. The most frequent operative finding was American Association for the Surgery of Trauma (AAST) grade 1 appendicitis in 303 patients (57%). Peritonitis was found in 109 patients (20.5%). Postoperative morbidity and mortality were 14.4% and 0%, respectively. Intra-abdominal abscess rate was 6.2%. An AAST grade of ≥2, a preoperative C-reactive protein level of >100 mg/dL, and diabetes mellitus were identified as independent risk factors for IAA in the multivariate analysis. Comparing LA and open appendectomy, there were no differences in IAA rates. After PSM, LA showed lower morbidity and shorter hospital stay. Conclusions Laparoscopic appendectomy is a safe approach and not related to a higher risk of IAA. Patients with an AAST grade of ≥2, a preoperative C-reactive protein level of >100, and diabetes mellitus have higher risk for postappendectomy IAA. Level of evidence Therapeutic/care management, level IV.
year | journal | country | edition | language |
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2020-10-02 | Journal of Trauma and Acute Care Surgery |