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RESEARCH PRODUCT

Unrecognised cardiovascular disease in type 2 diabetes: is it time to act earlier?

Eva GoncalvesovaNoémi NyolczasMartin ClodiMarek HonkaAndrej JanežLea DuvnjakRoger LehmannKristine DucenaElina Baltadzhieva-trendafilovaPriit PauklinNebojsa LalicChaim LotanIgor SergienkoJonas ČEponisAndrzej RynkiewiczGuntram SchernthanerCristian Guja

subject

Blood Glucoselcsh:Diseases of the circulatory (Cardiovascular) systemEndocrinology Diabetes and Metabolism10265 Clinic for Endocrinology and DiabetologyDiseaseType 2 diabetes030204 cardiovascular system & hematologySilent0302 clinical medicineRisk FactorsMass ScreeningAsymptomatic ; Atypical ; Cardiovascular disease ; Screening ; Silent ; Type 2 diabetes ; Unrecognised.Type 2 diabetesCardiovascular diseasePrognosisAsymptomatic3. Good health2712 Endocrinology Diabetes and MetabolismCardiovascular DiseasesScreeningmedicine.symptomCardiology and Cardiovascular Medicinemedicine.medical_specialtyPrognostic factor030209 endocrinology & metabolism610 Medicine & healthRisk AssessmentAsymptomatic2705 Cardiology and Cardiovascular Medicine03 medical and health sciencesPredictive Value of TestsInternal medicineDiabetes mellitusmedicineHumansHypoglycemic AgentsIntensive care medicineUnrecognisedbusiness.industrymedicine.diseaseEarly DiagnosisDiabetes Mellitus Type 2lcsh:RC666-7012724 Internal MedicineHeart failureAsymptomatic DiseasesCommentarybusinessAtypicalBiomarkers

description

Abstract Cardiovascular disease (CVD) is the most significant prognostic factor in individuals with type 2 diabetes (T2D). However, a significant number of individuals may develop CVD that does not present with the classic angina-related or heart failure symptoms. In these cases, CVD may seem to be ‘silent’ or ‘asymptomatic’, but may be more accurately characterised as unrecognised diabetic cardiac impairment. An initial step to raise awareness of unrecognised CVD in individuals with T2D would be to reach a consensus regarding the terminology used to describe this phenomenon. By standardising the terminologies, and agreeing on the implementation of an efficient screening program, it is anticipated that patients will receive an earlier diagnosis and appropriate and timely treatment. Given the availability of anti-diabetic medications that have been shown to concomitantly reduce CV risk and mortality, it is imperative to improve early identification and initiate treatment as soon as possible in order to enable as many patients with T2D as possible to benefit.

10.5167/uzh-208197https://www.zora.uzh.ch/id/eprint/208197/