6533b874fe1ef96bd12d60d1

RESEARCH PRODUCT

Zeitlicher Ablauf der ACTH-induzierten Stimulierung der Corticosteroidbiosynthese

D. Lommer

subject

endocrine systemmedicine.medical_specialtymedicine.drug_classChemistryTwo stepStimulationRat Adrenalschemistry.chemical_compoundEndocrinologyCorticosteroneInternal medicineTime coursemedicineCorticosteroidSecretionIncubationhormones hormone substitutes and hormone antagonists

description

The time course of ACTH action was studied during incubation of quartered rat adrenals by estimation of corticosterone production and secretion rates. The results suggest a two step action of ACTH during the acute stimulation of corticosteroid biosynthesis: A modest initial stimulation was observed within the first 30 min of exposure to ACTH which was overlapped by a marked secondary stimulation between 30 and 60 min.

yearjournalcountryeditionlanguage
1969-01-01
https://doi.org/10.1007/978-3-642-95126-8_75