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RESEARCH PRODUCT
Adherence to the Mediterranean diet is associated with better quality of life: data from the Osteoarthritis Initiative
Marco SolmiBrendon StubbsBrendon StubbsBrendon StubbsClaudio LuchiniMarianna NoaleStefania MaggiNicola Veronesesubject
0301 basic medicineMaleMultivariate analysisMediterranean dietCross-sectional studyMedicine (miscellaneous)MediterraneanLogistic regressionDiet MediterraneanBody Mass Index0302 clinical medicineMediterranean diet; depression; disability; pain; quality of life osteoarthritis initiativeQuality of lifeSurveys and Questionnaires030212 general & internal medicineNutrition and DieteticsCenter for Epidemiologic Studies Depression ScaleMiddle AgeddepressionFemalemedicine.medical_specialtyWOMACquality of life osteoarthritis initiativePaindepression Mediterranean diet quality of life osteoarthritis initiative pain disability03 medical and health sciencesNutritional Epidemiology and Public HealthMediterranean dietOsteoarthritismedicineHumansAged030109 nutrition & dieteticsbusiness.industryDietMediterranean diet; depression; disability; pain; quality of life osteoarthritis initiative; Aged; Body Mass Index; Cross-Sectional Studies; Energy Intake; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; North America; Osteoarthritis; Pain; Quality of Life; Socioeconomic Factors; Surveys and Questionnaires; Diet Mediterranean; Patient ComplianceCross-Sectional StudiesLogistic ModelsdisabilitySocioeconomic FactorsMultivariate AnalysisNorth AmericaPhysical therapyLinear ModelsQuality of LifePatient CompliancebusinessEnergy IntakeBody mass indexDemographydescription
BACKGROUND The Mediterranean diet has positively influenced various medical conditions, but only a paucity of studies has considered the relation between the Mediterranean diet and quality of life (QOL) among people living in North America. OBJECTIVE We investigated whether a higher adherence to the Mediterranean diet (aMED) was associated with better QOL and decreased pain, stiffness, disability, and depression in a large cohort of North Americans from the Osteoarthritis Initiative. DESIGN aMED was evaluated through a validated Mediterranean diet score categorized into quintiles. Outcomes of interest were QOL [assessed with the 12-Item Short-Form Health Outcome Survey (SF-12)]; disability, pain, and stiffness [assessed in both knees with the Western Ontario and McMaster Universities Arthritis Index (WOMAC)]; and depressive symptoms [assessed with the Center for Epidemiologic Studies Depression Scale (CES-D)]. RESULTS Of the 4470 participants (2605 women; mean age: 61.3 y), those with a higher aMED had significantly more favorable scores on all outcomes investigated (P < 0.0001 for all comparisons). After adjustment for potential confounders in linear regression analyses, a higher aMED was significantly associated with a higher SF-12 physical composite scale value (β: 0.10; 95% CI: 0.05, 0.15; P < 0.0001), lower WOMAC scores (except for stiffness), and lower CES-D scores (β: -0.05; 95% CI: -0.09, -0.01; P = 0.01). An adjusted logistic regression analysis, taking as reference those in the 2 highest quintiles of the aMED score, confirmed these findings. CONCLUSION Higher aMED is associated with better QOL and decreased pain, disability, and depressive symptoms. This trial was registered at clinicaltrials.gov as NCT00080171.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |