6533b874fe1ef96bd12d619c
RESEARCH PRODUCT
MRSA infection in the neonatal intensive care unit
Caterina MamminaCelestino BonuraD. CipollaMario Giuffrèsubject
Microbiology (medical)Methicillin-Resistant Staphylococcus aureusmedicine.medical_specialtyNeonatal intensive care unitMRSA infectionSettore MED/42 - Igiene Generale E ApplicataMicrobiologySettore MED/38 - Pediatria Generale E SpecialisticaVirologyIntensive Care Units NeonatalEpidemiologymedicinePrevalenceInfection controlHumansIntensive care medicineAntibacterial drugDeveloping CountriesInfection Controlbusiness.industryTransmission (medicine)Developed CountriesAustraliaInfant NewbornMRSA CA-MRSA HA-MRSA NICU epidemiology prevention controlOutbreakbiochemical phenomena metabolism and nutritionStaphylococcal Infectionsbacterial infections and mycosesUnited StatesAnti-Bacterial AgentsEuropeInfectious DiseasesEpidemiological MonitoringEpidemiological Monitoringbusinessdescription
Methicillin-resistant Staphylococcus aureus (MRSA) is well known as one of the most frequent etiological agents of healthcare-associated infections. The epidemiology of MRSA is evolving with emergence of community-associated MRSA, the clonal spread of some successful clones, their spillover into healthcare settings and acquisition of antibacterial drug resistances. Neonatal intensive care unit (NICU) patients are at an especially high risk of acquiring colonization and infection by MRSA. Epidemiology of MRSA in NICU can be very complex because outbreaks can overlap endemic circulation and make it difficult to trace transmission routes. Moreover, increasing prevalence of community-associated MRSA can jeopardize epidemiological investigation, screening and effectiveness of control policies. Surveillance, prevention and control strategies and clinical management have been widely studied and are still the subject of scientific debate. More data are needed to determine the most cost-effective approach to MRSA control in NICU in light of the local epidemiology.
year | journal | country | edition | language |
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2013-05-01 |