6533b874fe1ef96bd12d63bf
RESEARCH PRODUCT
Ductal lavage: a way of carefully tracing the breast-secreting duct
L. NapoliAntonio RussoValentina AgneseDaniele SantiniAntonio GiordanoClaudia AugelloGiuseppe BadalamentiSandra CascioValter GregorioNicola GebbiaPasqua Sandra SistoSalvatore FricanoValentina CalòViviana Bazansubject
medicine.medical_specialtyKidneyDuctal lavagebiologySettore MED/06 - Oncologia Medicabusiness.industrymedicine.medical_treatmentUrologyGeneral Medicinemedicine.diseaseSurgeryductal lavagemedicine.anatomical_structureRenal cell carcinomamedicineCarcinomaAdjuvant therapybiology.proteinPharmacology (medical)HemodialysisAntibodybusinessDuct (anatomy)description
Background: Breast cancer is the most commonly diagnosed neoplasia in women after nonmelanoma skin tumors. Unfortunately, present-day diagnostic methods are unable to identify the presence of a cancer until it has been developing for several years. Currently, ductal lavage seems to represent a new method of reaching an early diagnosis of breast cancer. Materials & methods: This study analyzed 30 patients with ages ranging from 40 to 55 years; and in 26 of these patients, we were able to obtain a sufficient quantity of material for cytological and biomolecular analysis. Results & conclusion: We propose an easy, reproducible method that makes it possible to obtain a detailed map of the nipple, in order to re-identify the duct orifice and take a series of repeated samples from it over a period of time. This procedure is a promising screening and translational research tool since it provides the quantity and quality of ductal fluid required for subsequent cytological and biomolecular analyses
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-05-01 | Therapy |