6533b882fe1ef96bd12db06f

RESEARCH PRODUCT

Additional file 1: of Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages

Ineta PopēnaArtūrs ĀBolsLīga SaulīteKārlis PleikoElīna ZandbergaKaspars JēkabsonsEdgars EndzeliņšAlicia LlorenteAija LinēUna Riekstiņa

subject

description

Experimental design of the THP-1 monocyte to macrophage differentiation showing the time points for the addition of EVs and stimulatory molecules. Below the experimental design, representative light microscopy images show morphology of THP-1 monocytes (M), M0 macrophages (M0), M1 macrophages (M1) and M2 macrophages (M2) (n = 4). Scale bar 100 μm. Representative flow cytometry dot plots show CD14, HLA-DR, CD206 and CD68 marker expression at M, M0, M1 and M2 stages. (JPG 1845 kb)

https://dx.doi.org/10.6084/m9.figshare.6181403.v1