Search results for " 16"

Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for prevention

2011

Objective. Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain. Methods. 1043 histological confirmed ICC cases diagnosed from 1940 to 2007 from six Spanish regions were assembled. HPV DNA detection was performed by SPF10 broad-spectrum PCR followed by deoxyribonucleic acid enzyme immunoassay and genotyping by reverse hybridization line probe assay (LiPA(25)) (version 1). Results. Of 1043 ICC cases, 904 were HPV DNA positive (adjusted prevalence: 89.1%). The eight most common types, in decreasing order, were HPV …

Potential impact of a nonavalent HPV vaccine on HPV related low-and high-grade cervical intraepithelial lesions: A referral hospital-based study in S…

2017

ABSTRACT While bivalent and quadrivalent HPV vaccines have been used for about 10 years, a nonavalent vaccine against HPV types 6/11/16/18/31/33/45/52 and 58 has been recently approved by FDA and EMA and is now commercially available. The objective of our study was to evaluate the potential impact of the nonavalent vaccine on HPV infection and related low- and high-grade squamous intraepithelial lesions (LSIL, HSIL), compared to the impact of the quadrivalent vaccine, in a female population living in Sicily (Italy). Low estimates of HPV vaccine impact were calculated as prevalence of HPV 6/11/16/18/31/33/45/52 and 58 genotypes, alone or in association, but excluding presence of other HPV ty…

Human papillomavirus infections and upper aero-digestive tract cancers: the ARCAGE study.

2013

Human papillomavirus (HPV) is causally implicated in a subset of cancers of the upper aero-digestive tract (UADT). Methods Associations between type-specific HPV antibodies were examined among 1496 UADT cancer case subjects and 1425 control subjects by estimating odds ratios (ORs) in logistic regression analyses adjusted for potential confounders. The agreement between serology and tumor markers of HPV infection, including presence of HPV DNA and p16 expression, were examined in a subset of tumors. Results HPV16 L1 seropositivity was associated with increased risk of oral cavity and oropharyngeal cancer (OR = 1.94, 95% confidence interval [CI] = 1.03 to 3.65; OR = 8.60, 95% CI = 5.21 to 14.…

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

2013

Estrogen receptor (ER)-negative tumors represent 20-30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry. The etiology and clinical behavior of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition. To identify susceptibility loci specific to ER-negative disease, we combined in a metaanalysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-up studies (6,514 cases and 41,455 controls), genotyped using a custom Illumina array, iCOGS, developed by the Collaborative Oncological Gene-environm…

Introduzione. Ritratto di città. Palermo musicale tra Cinque e Settecento.

2017

Si traccia brevemente lo stato degli studi sulla musica a Palermo tra Cinque e Seicento, a partire dagli articoli contenuti nel fascicolo, individuando nuove tendenze di ricerca e lacune. This essay aims at reconsidering scholarly studies about musical life in Palermo in 16-17th centuries; new paths of investigation are also discussed.

Ultraviolet-induced paramagnetic centers and absorption changes in singlemode Ge-doped optical fibers

2009

We investigated the laser-energy-density dependence of absorption changes and paramagnetic centers induced by a cw Ar+ laser operating at 5.1 eV, in both unloaded and H-2-loaded single mode Ge-doped optical fibers. The induced absorption is measured in the blue and near ultraviolet spectral range by using the 3.1 eV photoluminescence, ascribed to Ge lone pair center (GLPC), as an in situ probe source. We find that the Ge (1) center (GeO4-) is induced upon UV exposure by electron trapping on GeO4 precursors, where the free electrons are most likely produced by ionization of GLPC. Ge (1) is responsible of optical transmission loss of the fiber in the investigated range. Hydrogen loading stron…

Glorioso desēpeño de los mas illustres nombres de Maria y Ana, manifestado en las heroycas acciones de la mas Excelsa Reyna de España D. Mariana d…

1696

Port. amb orla tip. Caplletres ornades, vinyeta Sign.: œ4, œ2, A-D4, E2 Text amb notes marginals Reclams

Oracion funebre, en las exequias que en 11 de Iulio del año 1699 hizo la Santa Metropolitana Iglesia de Valencia al ... Señor Don Fray Iuan Thomas …

1699

El f. de làm. és el retrat de Tomàs de Rocabertí Port. con orla tip. Caplletres ornades, fris Sign.: [ ]3, œœ2, A-E4, F3 Text amb postil·les marginals Reclams

Llanto, consuelo, y alabanza, en la muerte de ... Luis de Borbòn, Delfin de Francia, hijo primogenito de Luis XIV el Grande ... en las exequias que c…

Port. amb orla tip Caplletres ornades, fris Sign.: [ ]4, A-B4, C1 Text amb postil·les marginals Reclams

Oracion funebre, que en las exequias ... Don Felipe V ... hizo la ... villa de Castellon de la Plana en su Iglesia Parroquial en el dia trece de seti…

Caplletres grav. i altres ornaments tip Sign.: *4, A-D4, E2 Text a 1 col. - Notes apeu de p. - Reclams