Search results for " 16"
showing 10 items of 871 documents
Copper Dynamics and Impact on Microbial Communities in Soils of Variable Organic Status
2008
International audience; The effect of soil organic status on copper impact was investigated by means of a microcosm study carried out on a vineyard soil that had been amended with varying types of organic matter during a previous long-term field experiment. Soil microcosms were contaminated at 250 mg Cu kg−1 and incubated for 35 days. Copper distribution and dynamics were assessed in the solid matrix by a sequential extraction procedure and in the soil solution by measuring total and free exchangeable copper concentrations. Copper bioavailability was also measured with a whole-cell biosensor. Modifications of microbial communities were assessed by means of biomass-C measurements and charact…
Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes
2019
γδ T lymphocytes represent ∼1% of human peripheral blood mononuclear cells and even more cells in most tissues of vertebrates. Although they have important anticancer functions, most current single-cell RNA sequencing (scRNA-seq) studies do not identify γδ T lymphocytes because their transcriptomes at the single-cell level are unknown. Here we show that high-resolution clustering of large scRNA-seq datasets and a combination of gene signatures allow the specific detection of human γδ T lymphocytes and identification of their T cell receptor (TCR)Vδ1 and TCRVδ2 subsets in large datasets from complex cell mixtures. In t -distributed stochastic neighbor embedding plots from blood and tumor sa…
Microbial diversity and structure are drivers of the biological barrier effect against Listeria monocytogenes in soil
2013
International audience; Understanding the ecology of pathogenic organisms is important in order to monitor their transmission in the environment and the related health hazards. We investigated the relationship between soil microbial diversity and the barrier effect against Listeria monocytogenes invasion. By using a dilution-to-extinction approach, we analysed the consequence of eroding microbial diversity on L. monocytogenes population dynamics under standardised conditions of abiotic parameters and microbial abundance in soil microcosms. We demonstrated that highly diverse soil microbial communities act as a biological barrier against L. monocytogenes invasion and that phylogenetic compos…
Impact of a new bio-pesticide produced by Paenibacillus sp. strain B2 on the genetic structure and density of soil bacterial communities
2007
The effect of paenimyxin, a new biopesticide produced by Paenibacillus sp. strain B2, on the density of soil bacterial communities was assessed by colony counting and by 16S rDNA and nirK quantitative polymerase chain reaction (PCR). Paenimyxin had a negative effect on the bacterial colony-forming unit (CFU) number, which was significantly reduced 2 and 4 days after treatment. The effect of paenimyxin on cultivatable bacteria was negligible 7 days after treatment. Approximately 107 16S rDNA sequences per gram of soil (dry weight) were detected by quantitative PCR in all samples. Paenimyxin did not affect the quantification of 16S rDNA or of the denitrifying bacterial community. In addition,…
La nouvelle réglementation européenne relative aux essais cliniques de médicaments à usage humain
2015
International audience
Molière
2021
Entrer comme il faut dans la nature des hommes, c'est faire la peinture de leurs caractères. En cela, Molière expose nos vices et nos ridicules pour nous aider à les corriger, tout en nous divertissant. Que seraient nos mœurs amoureuses sans Agnès et Arnolphe, Alcesteet Célimène, Pierrot et Charlotte ? Un miroir sans reflet d'où ne fuserait nul rire... Lever du rideau dans cinq minutes !
Le Théâtre néo-latin en France au XVIe siècle : études et anthologie
2020
International audience; Le théâtre néo-latin est longtemps resté en marge de l’histoire du théâtre français. Les pièces conservées ont souffert en effet de divers a priori : composées en latin par d’obscurs « Apollons de collège », elles ont semblé scolaires et didactiques ; écrites par des érudits qui ne songeaient pas à la scène, elles ont paru coupées de la création dramatique contemporaine. Depuis quelques décennies, cependant, bien des chercheurs mettent en question ces certitudes. Certains textes font l’objet d’un intense travail d’exégèse et d’édition, d’autres demeurent peu étudiés. L’heure n’est pas encore aux bilans. Le présent volume entend plutôt donner à découvrir une riche pro…
La Suzanna (1571) du Dijonnais Charles Godran
2020
International audience; No abstract
Se fier aux apparences. Gestes bienséants et gestes malséants dans l’œuvre épigrammatiques de Nicolas Bourbon
2019
International audience; No abstract
Neo-Latin Literature - France: The Sixteenth Century: Literature
2014
OS internat; International audience; no abstract