Search results for " 18"

showing 10 items of 4487 documents

Differences in incidence and survival of oral cavity and pharyngeal cancers between Germany and the United States depend on the HPV-association of th…

2017

Abstract Introduction The epidemiology of squamous cell oral cavity and pharyngeal cancers (OCPC) has changed rapidly during the last years, possibly due to an increase of human papilloma virus (HPV) positive tumors and successes in tobacco prevention. Here, we compare incidence and survival of OCPC by HPV-relation of the site in Germany and the United States (US). Materials and methods Age-standardized and age-specific incidence and 5-year relative survival was estimated using data from population-based cancer registries in Germany and the US Surveillance Epidemiology and End Results (SEER) 13 database. Incidence was estimated for each year between 1999 and 2013. Relative survival for 2002…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPopulationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesYoung AdultAll institutes and research themes of the Radboud University Medical Center0302 clinical medicinePharyngeal cancerGermanyEpidemiologySurveillance Epidemiology and End ResultsMedicineHumans030212 general & internal medicineeducationAgededucation.field_of_studyRelative survivalbusiness.industryIncidence (epidemiology)IncidencePharynxPapillomavirus InfectionsCancerPharyngeal NeoplasmsMiddle Agedmedicine.diseaseSurvival AnalysisUnited StatesSurgeryTumor Virus Infectionsmedicine.anatomical_structureOncology030220 oncology & carcinogenesisFemaleMouth NeoplasmsOral SurgerybusinessDemography
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Familial ring (18) mosaicism in a 23-year-old young adult with 46,XY,r(18) (::p11→q21::)/46,XY karyotype, intellectual disability, motor retardation …

2010

We report on a 23-year-old man with craniofacial findings of the holoprosencephaly spectrum disorder (microcephaly, hypotelorism, depressed nasal bridge, single median maxillary central incisor), fusion of C2-C3 vertebrae, intellectual disability, and severe sleep apnea. Chromosome analysis of blood lymphocytes showed 75% ring (18) cells and 25% normal cells, karyotype mos 46,XY,r(18)(::p11→q21::)[75]/46,XY[25]. His mother was phenotypically normal except for a double ureter and bifid renal pelvis as in his son. She had a supernumerary ring (18) in 10% of blood lymphocytes, karyotype mos 47,XX,+r(18)(::p11→q21::)[10]/46,XX[90]. Familial ring (18) is a rare cytogenetic abnormality. This is t…

AdultMaleGeneticsMonosomyMicrocephalyMosaicismRing chromosomeMothersAneuploidyKaryotypeAnatomyMotor ActivityBiologymedicine.diseasePhenotypeChromosome 18Intellectual DisabilityKaryotypingGeneticsRing 18medicineHumansFemaleSupernumeraryGenetics (clinical)American Journal of Medical Genetics Part A
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The main trends in the palaeodemography of the 7th-18th century population of Latvia

2006

The study represents palaeodemographic research of osteological material of 3304 individuals from the funds of the Anthropological Laboratory of the Institute of History of the University of Latvia in Riga, dating from the 7 th to the 18 th century AD. Compensated life expectancy at birth is varying between 20.3 and 22.2 years during the research period. Crude mortality has changed between 49.3 and 45 %o. In the early period (7 th - 13 th century) there is a significant male prevalence (2.2 - 1.4); female life expectancy at the age of 20 is on average 6.6 years less than for males. This difference decreases to 5.4 years in the 13 th - 18 th century. According to historical demography, femal…

AdultMaleHistoryAdolescentPopulation DynamicsPopulationDemographic transitionReproductive ageHistory 18th CenturyHistory 17th CenturyAge DistributionLife ExpectancyBody SizeHumansMortalitySex DistributionBirth RateChildeducationEcology Evolution Behavior and SystematicsDemographyHistory 15th CenturyFamily Characteristicseducation.field_of_studyLife spanInfant NewbornInfantPaleontologyHistorical demographyGeneral MedicineMiddle AgedLatviaHistory MedievalChild mortalityHistory 16th CenturyFemale life expectancyChild PreschoolAnthropologyLife expectancyFemaleAnimal Science and ZoologyDemographyAnthropologischer Anzeiger
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Translocation (X;18) in a Biphasic Synovial Sarcoma with Morphologic Features of Neural Differentiation

1998

The authors report a recurred neoplasm showing distinctive histologic, immunophenotypic, and ultrastructural features characteristic of biphasic synovial sarcoma with neural differentiation. The features include areas with a growth pattern of densely packed spindle cells in irregularly intersecting, broad fascicles, diffuse vimentin and HBA 71 immunoreactivity, expression of S-100 protein, and other neural markers. Moreover, areas with glandular structures and cellular expression of cytokeratin and epithelial membrane antigen were noted. Additionally, areas of neural-like growth pattern were positive for neuron-specific enolase, HNK-1, and protein gene product 9.5. Furthermore, cytogenetic …

AdultMaleLung NeoplasmsX ChromosomeBiphasic Synovial SarcomaEnolaseSoft Tissue NeoplasmsChromosomal translocationVimentinPolymerase Chain ReactionTranslocation GeneticImmunophenotypingPathology and Forensic MedicineGene productSarcoma SynovialCytokeratinTumor Cells CulturedmedicineHumansMolecular BiologyIn Situ Hybridization FluorescenceNeuronsmedicine.diagnostic_testbiologyChemistryCell DifferentiationPatellaCell BiologyMolecular biologyReverse transcription polymerase chain reactionKaryotypingbiology.proteinChromosomes Human Pair 18Fluorescence in situ hybridizationDiagnostic Molecular Pathology
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Factors Associated with Providers' Work Engagement and Burnout in Homeless Services: A Cross-national Study

2021

Contains fulltext : 232434.pdf (Publisher’s version ) (Closed access) The complexity of homeless service users' characteristics and the contextual challenges faced by services can make the experience of working with people in homelessness stressful and can put providers' well-being at risk. In the current study, we investigated the association between service characteristics (i.e., the availability of training and supervision and the capability-fostering approach) and social service providers' work engagement and burnout. The study involved 497 social service providers working in homeless services in eight different European countries (62% women; mean age = 40.73, SD = 10.45) and was part o…

AdultMaleSocial WorkHealth (social science)Applied psychologySupervisionBurnoutHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesNegatively associatedProfessionalBurnoutTrainingHumans0501 psychology and cognitive sciencesService userBurnout ProfessionalApplied PsychologyService (business)030505 public healthServiceSocial workWork engagement05 social sciencesMultilevel model1. No povertyPublic Health Environmental and Occupational HealthHomelessnessHomeless PersonsBurnout; Capabilities; Homelessness; Service; Supervision; Training; Adult; Female; Humans; Male; Social Work; Work Engagement; Burnout Professional; Homeless PersonsWork EngagementCapabilitiesIll-Housed PersonsFemale0305 other medical sciencePsychology050104 developmental & child psychologyCross national
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More than a leap of faith: the impact of biological and religious correlates on reproductive behavior.

2004

Using a conceptual model that integrates both social and biomedical factors of causation, this paper tries to delineate the pathways through which the reproductive characteristics of a multidenominational community are characterized. In total, 5513 historical entries from family reconstitution were available. Selection of data was guided by the inclusion of information about religious affiliation. Only married couples with children as well as single mothers with the relevant information were considered. Of these, 1855 entries were of Roman Catholic (C), 1143 of Lutheran/Protestant (L/P2), and 609 of Reformed Calvinist (R) denomination. The analysis documented differential nuptiality and fer…

AdultMalemedia_common.quotation_subjectFertilityReproductive BehaviorHistory 18th CenturyLeap of faithBiological FactorsProtestantismSociologyGermanyGeneticsHumansFamilySociologyCausationMarriageSociocultural evolutionGenetics (clinical)Ecology Evolution Behavior and Systematicsmedia_commonHistorical demographyHistorical ArticleHistory 19th CenturySingle mothersHistory 20th CenturyModels TheoreticalReligionParitySocioeconomic FactorsFemaleSeasonsSocial psychologyMaternal AgeHuman biology
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Variable geographic distribution of Blastocystis subtypes and its potential implications.

2012

Blastocystis is a common intestinal micro-eukaryote found in both humans and non-human hosts and known to be genetically very diverse. It has been divided into numerous subtypes (STs), nine of which have been identified in humans to date. Surveys of ST prevalence have started to emerge over the past few years but to date no data are available for any African country except Egypt and Tanzania. In this study, we determined the prevalence of Blastocystis STs in populations from Libya, Liberia and Nigeria, as well as expanding the dataset available for the UK. A total of 356 Blastocystis STs were identified in this study, 271 from the UK, 38 from Libya, 25 from Liberia and 22 from Nigeria. SSU …

AdultMalemedicine.medical_specialtyAdolescentGenotypeVeterinary (miscellaneous)Blastocystis InfectionsDNA RibosomalYoung AdultEpidemiologyGenetic variationGenotypemedicinePrevalenceRNA Ribosomal 18SHumansChildBlastocystisGenetic diversityMolecular EpidemiologybiologyMolecular epidemiologyGenetic VariationDNA Protozoanbiology.organism_classificationUnited KingdomPhylogeographyPhylogeographyInfectious DiseasesTanzaniaGeographyInsect ScienceAfricaBlastocystisParasitologyFemaleDemographyActa tropica
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Lifetime, 5-year and past-year prevalence of homelessness in Europe: a cross-national survey in eight European nations

2019

ObjectivesTo examine the lifetime, 5-year and past-year prevalence of homelessness among European citizens in eight European nations.DesignA nationally representative telephone survey using trained bilingual interviewers and computer-assisted telephone interview software.SettingThe study was conducted in France, Ireland, Italy, the Netherlands, Poland, Portugal, Spain and Sweden.ParticipantsEuropean adult citizens, selected from opt-in panels from March to December 2017. Total desired sample size was 5600, with 700 per country. Expected response rates of approximately 30% led to initial sample sizes of 2500 per country.Main outcome measuresHistory of homelessness was assessed for lifetime, …

AdultMalemedicine.medical_specialtyTime FactorsAdolescent[SDV]Life Sciences [q-bio]prevalenceService useSociodemographic dataHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesHealth servicesYoung Adult0302 clinical medicineRisk FactorsSurveys and QuestionnairesmedicineHumans1724030212 general & internal medicine150610. No inequalitySociodemographic datahomelessnessAgedOriginal ResearchAged 80 and overbusiness.industryeuropean adult citizensEurope; homelessness; prevalence; public healthCross national surveyPublic health1. No povertyGeneral MedicineMiddle Aged3. Good healthTelephone surveyEuropeTelephone interviewSocioeconomic FactorsSample size determinationIll-Housed PersonsLinear ModelsFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiePublic Healthbusiness030217 neurology & neurosurgeryDemographyBMJ Open
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Serum levels of interleukin-18 and s-ICAM-1 in patients affected by psoriasis: preliminary considerations.

2003

Objective To find new aspects of the systemic involvement of the Immune System in psoriasis, we determined serum levels of interleukin-18 (IL-18) (Th1-inducing factor cytokine), CD30 (Th2 marker) and sICAM-1 (adhesion molecule). In addition we evaluated the correlation between these molecules and psoriasis area and severity index (PASI). Background Psoriasis is associated to an overexpression of Th1 cytokines and a relative underexpression of Th2 cytokines. IL-18 plays an important role in inducing Th1 response because it is a potent inductor of synthesis of IFN-γ, TNF and other mediators. The two major sources of IL-18 are monocytes and macrophages but also human keratinocytes constitutive…

AdultMalemedicine.medical_treatmentKi-1 AntigenDermatologySeverity of Illness IndexImmune systemPsoriasis Area and Severity IndexPsoriasisMedicineHumansPsoriasisICAM-1business.industryCase-control studyInterleukin-18medicine.diseaseIntercellular Adhesion Molecule-1Infectious DiseasesCytokineCase-Control StudiesImmunologyInterleukin 18Tumor necrosis factor alphaFemalebusinessJournal of the European Academy of Dermatology and Venereology : JEADV
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European perspective on the 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroi…

2018

The American Thyroid Association (ATA) management guidelines for patients with thyroid nodules and differentiated thyroid cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. European experts frequently have different perspectives, given epidemiological, technological/methodological, practice organization, and medicolegal differences between the respective regions.Divergent viewpoints were the focus of an invited symposium organized by the European Association of Nuclear Medicine involving 17 European thyroidologists, four ATA Guidelines Taskforce members, and…

AdultThyroid nodulesendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismMedizinThyroid Gland030209 endocrinology & metabolismrisk stratificationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciences0302 clinical medicineEndocrinologyAll institutes and research themes of the Radboud University Medical CenterInternal medicineHumansMedicineThyroid NeoplasmsThyroid NoduleguidelinesDisease management (health)differentiated thyroid cancer (DTC)Thyroid cancerAdult patientsbusiness.industrythyroid nodulesPerspective (graphical)Thyroidmedicine.diseaseUnited Statesdifferentiated thyroid cancer (DTC); disease management; guidelines; pathology; risk stratification; thyroid nodules; Endocrinology Diabetes and Metabolism; EndocrinologyEuropeDiabetes and Metabolismmedicine.anatomical_structuredisease management030220 oncology & carcinogenesisPractice Guidelines as TopicRisk stratificationpathologybusiness
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