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Assessment of genetically modified maize GA21 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐005)
2017
Efsa Panel On Genetically Modified Organisms (gmo) Requestor: European Commission (DG SANTE)Question number: EFSA-Q-2016-00714Correspondence; Following the submission of application EFSA-GMO-RX-005 under Regulation (EC) No 1829/2003 from Syngenta Crop Protection NV/SA, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of authorisation application of the herbicide-tolerant genetically modified maize GA21. The data received in the context of this renewal application contained post-market environmental monitoring reports, a systematic search and eval…
Optimization of Synthetic Media Composition for Kluyveromyces marxianus Fed-Batch Cultivation
2021
The Kluyveromyces marxianus yeast recently has gained considerable attention due to its applicability in high-value-added product manufacturing. In order to intensify the biosynthesis rate of a target product, reaching high biomass concentrations in the reaction medium is mandatory. Fed-batch processes are an attractive and efficient way how to achieve high cell densities. However, depending on the physiology of the particular microbial strain, an optimal media composition should be used to avoid by-product synthesis and, subsequently, a decrease in overall process effi-ciency. Thus, the aim of the present study was to optimise the synthetic growth medium and feeding solution compositions (…
What a line can say : Investigating the semiotic potential of the connecting line in data visualizations
2020
The line is a graphical element widely used in data visualizations, its purpose often being to signal a connection between other visual elements. Based on social semiotic theory, this article investigates what semiotic functions connecting lines can have and how these functions can be related to variations in form. The results show that, in addition to the basic function of connecting elements, such lines can also indicate the level of certainty, direct the viewer to read the information either as a narrative or a conceptual claim, indicate patterns of cohesion, and regulate the viewer’s position. These findings allow for further empirical research on the formation of visual conventions.
Exploring how social interactions influence regulators and innovators: The case of regulatory sandboxes
2020
Like incubators, regulatory sandboxes constitute a prominent mechanism to enable entrepreneurial activities that guide financial technology (FinTech) firms through regulatory frameworks in the financial industry. Because they are new, there is a lack of research on regulatory sandboxes; most studies have investigated legal aspects while overlooking the management perspective. To address this gap, this paper builds on incubation research studies to explore how social interactions within regulatory sandboxes influence the practices of regulators and regulatees, using social capital theory. An exploratory-abductive approach is adopted, using data collected from 16 semi-structured interviews. T…
Orchestrated learning: creating a company-specific production system (XPS)
2021
Purpose Companies create company-specific production systems (XPS) by tailoring generic concepts to fit their unique situation. However, little is known about how an XPS is created. This paper aims to provide insights into the creation of an XPS. Design/methodology/approach A retrospective case study was conducted in a Norwegian multinational company over the period 1991–2006, using archival data and interviews. Findings The development of the XPS did not start with a master plan. Instead, dispersed existing initiatives were built upon, along with an external search for novel ideas. Widespread experimentation took place, only later to be combined into a coherent approach. Once established,…
Towards criteria for sustainable process selection: On the modelling of pure subtractive versus additive/subtractive integrated manufacturing approac…
2017
Additive Manufacturing (AM) processes can be counted among the disruptive technologies that are capable of transforming conventional manufacturing routes. The ability to create complex geometries, the reduction in material scraps during manufacturing, and the light-weighting due to the think-additive redesign of the components represent the main points of strength of AM. However, for some applications (such as the production of metal components for the automotive and aerospace industries), the surface finishing and dimensional/geometrical part tolerancing that can be achieved via AM processes might not be adequate to satisfy the imposed product specifications, and finish machining operation…
Influence of processing parameters and initial temper on Friction Stir Extrusion of 2050 aluminum alloy
2017
Abstract Friction Stir Extrusion is an innovative production technology that enables direct wire production via consolidation and extrusion of metal chips or solid billets. During the process, a rotating die is plunged into a cylindrical chamber containing the material to be extruded. The stirring action of the tool produces plastic flow in the extrusion chamber, densifying and heating the charge so that finally, fully dense rods are extruded. Experiments have been carried out in order to investigate the influence of process parameters and initial temper of the base material on the process variables and on the extrudates’ mechanical properties.