Search results for " 4"

showing 10 items of 3131 documents

Beta-apo-8'-carotenal, but not beta-carotene, is a strong inducer of liver cytochromes P4501A1 and 1A2 in rat

1996

35 ref.; International audience

ALIMENTATION DES ANIMAUXRAT[SDV.BID]Life Sciences [q-bio]/BiodiversityCYTOCHROME P 450[SDV.BID] Life Sciences [q-bio]/Biodiversity
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Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: Insights from the LUNG SAFE study

2020

Abstract Background Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence o…

ARDSmedicine.medical_treatment030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineHyperoxemiaHypoxemialaw.inventionHypoxemia0302 clinical medicinelawFraction of inspired oxygenOxygen therapyPrevalenceMedicineHypoxiaAcute respiratory distress syndrome; Hyperoxemia; Hyperoxia; Hypoxemia; Hypoxia; Invasive mechanical ventilation; Mortality; Oxygen therapy;Respiratory Distress SyndromeHyperbaric OxygenationAcute respiratory distress syndromeRespirationlcsh:Medical emergencies. Critical care. Intensive care. First aidHyperoxemiaIntensive care unitIntensive Care UnitsAnesthesiaArtificialmedicine.symptomHumanArtificial ventilationAcute respiratory distress syndrome; Hyperoxemia; Hyperoxia; Hypoxemia; Hypoxia; Invasive mechanical ventilation; Mortality; Oxygen therapyIntensive Care UnitHyperoxiaNO03 medical and health sciencesIntensive careSettore MED/41 - ANESTESIOLOGIAHumansInvasive mechanical ventilationMortalitybusiness.industryResearchRespiratory Distress Syndrome Adultlcsh:RC86-88.9medicine.diseaseOxygen therapyRespiration Artificialrespiratory tract diseasesOxygenlnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]030228 respiratory systembusiness
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Flexibility in otherwise consistent non-breeding movements of a long-distance migratory seabird, the long-tailed skua

2017

Quantifying within- and between-individual variation in animal migration strategies is a first step towards our understanding of the ability of migrants to adjust to changes in the en - vironment. We studied consistency (or, conversely, flexibility) in movement patterns at large (>1000 km) to meso-scales (100−1000 km) during the non-breeding season of the long-tailed skua Stercorarius longicaudus, a long-distance migratory Arctic seabird, using light-based geolocation. We obtained 97 annual tracks of 38 individuals and quantified similarity between routes. Overall, tracks of the same individual were generally within about 200 to 300 km of their previous year’s route, and more similar than t…

ATLANTIC0106 biological sciencesEnvironmental changeIndividual consistency · Repeatability · Stercorarius longicaudus · Seabirds · Tracking · Non-breeding movements · Flexibility:Zoology and botany: 480 [VDP]CONSERVATIONMODELSTRANS-EQUATORIAL MIGRATIONAquatic Science010603 evolutionary biology01 natural sciencesSkuaStercorarius longicaudusOnderzoeksformatieOCEANALBATROSSESindividual consistencyDISPERSALbiology.animalRepeatability:Zoologiske og botaniske fag: 480 [VDP]Ecology Evolution Behavior and SystematicsEcologybiologyEcology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]010604 marine biology & hydrobiologyFlexibility (personality)trackingbiology.organism_classificationTERNS STERNA-PARADISAEASeabirdsGeolocation[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]GeographyArcticWildlife Ecology and ConservationStercorarius longicaudusNAVIGATIONWIASnon-breeding movementsBiological dispersalSeabirdFlexibilityBEHAVIOR
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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First M87 Event Horizon Telescope Results. VIII. Magnetic Field Structure near The Event Horizon

2021

Full list of authors: Akiyama, Kazunori; Algaba, Juan Carlos; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Benson, Bradford A.; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond; Boland, Wilfred; Bouman, Katherine L.; Bower, Geoffrey C.; Boyce, Hope Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broderick, Avery E.; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Chesler, Paul M.; Cho, Ilje; Christian, Pierre; Conway, John E.…

AccretionKinoAstrophysics - astrophysics of galaxiesAstrophysics::High Energy Astrophysical PhenomenaAstronomy19641347FOS: Physical sciences479Astrophysics::Cosmology and Extragalactic AstrophysicsF500870126101 natural sciences7. Clean energyAstrophysics - high energy astrophysical phenomena994MagnetohydrodynamicsRelativistic jets 14 162 479 870 886 994 1964 1261 1278 1335 1347 13900103 physical sciencesJetsPolarimetryRadiative transferPlasma astrophysicsRadio jets010303 astronomy & astrophysicsAstrophysics::Galaxy Astrophysics162High Energy Astrophysical Phenomena (astro-ph.HE)Physics1278Event horizons1335010308 nuclear & particles physicsBlack holesChatterjee14886Astronomy and AstrophysicsCreative commons139013. Climate actionSpace and Planetary ScienceAstrophysics of Galaxies (astro-ph.GA)Magnetic fieldsKerr black holesFish <Actinopterygii>Relativistic jetsHumanities
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Mediated action in teachers’ discussions about mathematics tasks

2012

Published version of an article in the journal: ZDM. Also available from the publisher at: http://dx.doi.org/10.1007/s11858-012-0423-0 This paper presents analyses of teachers’ discussions within mathematics teaching developmental research projects, taking mediation as the central construct. The relations in the so-called ‘didactic triangle’ form the basic framework for the analysis of two episodes in which upper secondary school teachers discuss and prepare tasks for classroom use. The analysis leads to the suggestion that the focus on tasks places an emphasis on the task as object and its resolution as goal; mathematics has the role of a mediating artefact. Subject content in the didactic…

Action (philosophy)General MathematicsMediationPedagogyMathematics educationmediationmathematics teaching developmenttasksPsychologydidactic triangleVDP::Mathematics and natural science: 400::Mathematics: 410EducationVDP::Social science: 200::Education: 280::Subject didactics: 283
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The pedagogical development of an international teacher in the cultural context of Finnish CLIL home economics

2016

This thesis draws on content and language integrated learning (CLIL) as a methodological innovation in language education. In order to become competent CLIL teachers in 21st century, however, teachers should not merely have expertise knowledge in their own teaching fields but take pedagogical tact into consideration. The aim of this qualitative action research is to understand: (1) How an international teacher from Taiwan utilized the theoretical framework of CLIL 4Cs and (2) How 4Cs were used as a support to develop pedagogical tact in CLIL home economics classes in a Finnish lower secondary school. The action research approach and process were conducted in two cycles that included plannin…

Action ResearchToimintatutkimusCLIL Home EconomicsTaiwanopetusCLIL 4Csmonikulttuurisuuspedagogiikkavieraskielinen opetusSuomiPedagogical TactkotitalousCross-Cultural ExperienceFinland
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Educating to inspire active learning approaches in mathematics in Norwegian universities

2021

This is a report of an analysis of some of the data generated by a national survey of teaching approaches used in higher education mathematics courses. The overall purpose of the survey was to explore how widespread is the use of teaching approaches that might promote students’ active learning of mathematics. The paper includes a brief presentation of the authors meaning of the expression “teaching actions that have the potential to promote active learning”. The analysis focuses on the responses of 95 lecturers working in 13 Norwegian HE institutions. The goal is to expose underlying patterns in lecturers’ responses to questions about the teaching actions they may incorporate in their pract…

Active learninglanguageMathematics educationComputingMilieux_COMPUTERSANDEDUCATIONNorwegianVDP::Mathematics and natural science: 400::Mathematics: 410language.human_language
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Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina

2020

This work addresses the way in which Argentine Fat Activism has developed, in recent years, the demand for depathologization of fatness, taking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. First, the contemporary fat body is described in terms of stigma and discrimination, especially in the health field. Then, they refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspective, Fat Studies and Fat Activism. Lastly, a series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were considered, …

Activismo gordo en Argentina Contrera [1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos]in recent yearsDespatologización.Human RightsFat Studiesespecially in the health field. Thenthe contemporary fat body is described in terms of stigma and discriminationthey refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspectivea series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were consideredCOVID-19:SOCIOLOGÍA [UNESCO]and highlights the innovation of the local turn in the current context of pandemic. Estudios Sobre GorduraActivismo Gordo1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina ContreraDerechos HumanosDepathologization 175 188focusing on the claim of depathologizationUNESCO::SOCIOLOGÍAFat Studies and Fat Activism. Lastlythe demand for depathologization of fatnesstaking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. FirstFat ActivismLaura This work addresses the way in which Argentine Fat Activism has developed
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A conceptual model of feedback mechanisms in adjusted affordances – Insights from usage of a mental mobile health application

2023

Affordance theory provides one of the most prominent lenses through which the socio-technical aspects of a system’s use can be investigated and understood. In this context, the literature has proposed that perceived and actualized affordances may be adjusted over time. Yet, how the adjustment of affordances occurs has not been explained in detail. Thus, in this article, we develop a conceptual model of feedback mechanisms that includes a more explicit description of how affordances are perceived by users, whether actualized and adjusted. With the model, we introduce the central concept of a generative base, out of which affordance perceptions emerge and which can be updated through affordan…

ActualizationComputer Networks and CommunicationsMental ModelsPerception000 Informatik Informationswissenschaft allgemeine Werke::000 Informatik Wissen Systeme::004 Datenverarbeitung; InformatikLibrary and Information SciencesFeedback MechanismsVDP::Matematikk og Naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420AffordancesInformation Systems004
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