Search results for " ACTIVATION"

showing 10 items of 1535 documents

Very high specific activity erbium 169Er production for potential receptor-targeted radiotherapy

2019

Erbium 169Er is one of the most interesting radiolanthanides for new potential receptor-targeted β− therapy applications due to its low energy β− emissions, very low intensity ɣ rays and the possibility to use 68Ga or 44Sc as companion for diagnostic in a theranostics approach. Currently it can be produced in reactors through the neutron activation of highly enriched 168Er. The low specific activity of the produced carrier-added 169Er is limiting its use for receptor-targeted therapy. Nonetheless it is used for radiosynoviorthesis of small joints. The aim of this work is to develop a new large-scale production method for the supply of very high specific activity 169Er. Highly enriched 168Er…

Nuclear and High Energy PhysicsHIGH SPECIFIC ACTIVITIESMaterials scienceTargeted Radiotherapychemistry.chemical_elementLASER IONIZATION7. Clean energy030218 nuclear medicine & medical imaginglaw.inventionErbium03 medical and health sciences0302 clinical medicinePRECLINICAL STUDIESlaw[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Production (economics)HIGH SPECIFIC ACTIVITYIrradiationInstrumentationComputingMilieux_MISCELLANEOUSATOM LASERSRadiochemistrySELECTIVE IONIZATIONNuclear reactorERBIUMRESONANT LASER IONIZATIONLARGE SCALE PRODUCTIONSchemistryHigh specific activityER-169030220 oncology & carcinogenesisSEPARATION EFFICIENCYTARGETED RADIOTHERAPYIONIZATIONSpecific activityRECEPTOR-TARGETED THERAPYNeutron activationNUCLEAR REACTORSNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
researchProduct

The discovery of nuclear fission 50 years ago a few remarks

1990

Abstract  A historical account on the details of the discovery of nuclear fission in 1939 is given.

Nuclear physicsNuclear Energy and EngineeringNuclear fissionChemistryHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthRadiology Nuclear Medicine and imagingPollutionSpectroscopyAnalytical ChemistryNeutron activationJournal of Radioanalytical and Nuclear Chemistry Articles
researchProduct

Toward large-area targets for “TRAKULA”

2011

Abstract TRAKULA ( Tra nsmutationsrelevante k ernphysikalische U ntersuchungen l anglebiger A ktinide, i.e., nuclear physical investigations of long-lived actinides with relevance to transmutation) is a joint research project of the German Federal Ministry of Science and Education (BMBF) on nuclear physics investigations with modern scientific, technological and numerical methods. Experiments concerning the transmutation of radioactive waste are a central topic of the project. For this, large-area samples (≥40 cm 2 ) of 235,238 U and 239,242 Pu compounds are required for the calibration of fission chambers and for fission yield measurements. Another topic within the project requires large-a…

Nuclear physicsPhysicsNuclear and High Energy PhysicsNuclear transmutationFissionNuclear engineeringRadioactive wasteFission product yieldSurface finishActinideNeutron activation analysisInstrumentationElectrochemical cellNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
researchProduct

Priming effects of an olfactory food cue on subsequent food-related behaviour

2013

International audience; Studies in cognitive psychology have highlighted a link between perception and action, by revealing the non-conscious influence that a cue can have on thinking and doing. The present study aimed at exploring whether an olfactory food cue could have an impact on food choices. We chose fruity odours as olfactory food cues, in order to examine if this kind of olfactory cue could lead individuals to choose fruit and vegetables. In the first experiment, 58 participants were assigned randomly to either a control or a melon-scent condition. In the melon-scent condition, they were unobtrusively exposed to a melon odorant in a waiting room, while in the control condition the …

Nutrition and Dieteticsmedia_common.quotation_subject05 social sciencesfood and beverages050109 social psychologyContext (language use)food choiceimplicit concept activation050105 experimental psychologyTask (project management)Food cuePerceptionFood choiceLexical decision taskodour0501 psychology and cognitive sciencesolfactory food cuePsychologyprimingSocial psychologyPriming (psychology)[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Sciencemedia_commonCognitive psychology
researchProduct

Homogeneous Metal-Based Catalysis in Supercritical Carbon Dioxide as Reaction Medium

2016

Above 31.1 degrees C and 73.8 bar, carbon dioxide reaches the supercritical state, being transformed into a fluid (scCO(2)) that has attracted interest in the last few decades as reaction medium for several transition-metal-catalyzed organic transformations. The main feature of this fluid rests on its capability to dissolve large amounts of other gases such as hydrogen, carbon monoxide, ethylene, or even methane and light alkanes. In this manner, very high concentrations of these reactants are available for catalysis. In this contribution a review of the main achievements of the use of transition-metal complexes as catalysts in scCO(2) is presented.

Olefin metathesisInorganic chemistryHomogeneous catalysis010402 general chemistry01 natural sciencesC-C bond formationCatalysisMethaneCatalysischemistry.chemical_compoundSupercritical carbon dioxideOxidationC-H activationCycloadditionElectrochemical reduction of carbon dioxideSupercritical carbon dioxide010405 organic chemistryChemistryGeneral ChemistryHomogeneous catalysisSupercritical fluid0104 chemical sciencesCarbon dioxideHydroformylationHydrogenationCarbon monoxide
researchProduct

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

2012

Membrane microvesicle shedding is an active process and occurs in viable cells with no signs of apoptosis or necrosis. We report here that microvesicles shed by oligodendroglioma cells contain an ‘aggrecanase’ activity, cleaving aggrecan at sites previously identified as targets for adamalysin metalloproteinases with disintegrin and thrombospondin domains (ADAMTSs). Degradation was inhibited by EDTA, the metalloproteinase inhibitor GM6001 and by tissue inhibitor of metalloproteinases (TIMP)-3, but not by TIMP-1 or TIMP-2. This inhibitor profile indicates that the shed microvesicles contain aggrecanolytic ADAMTS(s) or related TIMP-3-sensitive metalloproteinase(s). The oligodendroglioma cells…

OligodendrogliomaMembrane vesicleRA rheumatoid arthritisADAMTSMatrix metalloproteinaseCell Physiological PhenomenaAdamalysin03 medical and health sciences0302 clinical medicineSettore BIO/10 - BiochimicaEndopeptidasesHumansAggrecansADAM adamalysinADAMTS a disintegrin and metalloproteinase with thrombospondin motifsMolecular BiologyMetalloproteinase030304 developmental biologyAggrecanaseTissue Inhibitor of Metalloproteinase-3MEF mouse embryonic fibroblasts0303 health sciencesMetalloproteinaseChemistryBrief ReportMVs microvesiclesADAMTSMicrovesicleCytoplasmic VesiclesDipeptidesFibroblastsMolecular biologyRecombinant ProteinsMicrovesiclesECM extracellular matrixMembrane vesiclesCell biologyEnzyme ActivationMMP matrix metalloproteinaseADAM ProteinsADAMTS4030220 oncology & carcinogenesisProteolysisADAMTS5 ProteinRheumatic FeverTIMP tissue inhibitor of metalloproteinaseAggrecan
researchProduct

Rituximab in vivo purging is safe and effective in combination with CD34-positive selected autologous stem cell transplantation for salvage therapy i…

2002

The purpose of this study was to evaluate feasibility and efficacy of Rituximab included into a sequential salvage protocol for CD20(+) B-NHL in relapse or induction failure. Twenty-seven patients with CD20(+) B-NHL in relapse or induction failure received Rituximab combined with DexaBEAM (R-DexaBEAM) for stem cell mobilization. Additional ex vivo selection of CD34-positive cells was performed using the CliniMacs device. Two doses of Rituximab were included in the high-dose therapy regimen (HDT). R-DexaBEAM was well tolerated and 26 of 27 patients mobilized sufficient numbers of CD34(+) blood stem cells. Application of R-DexaBEAM resulted in significant depletion of peripheral B cells. No t…

OncologyAdultMalemedicine.medical_specialtyLymphoma B-CellSalvage therapyAggressive lymphomaAntigens CD34Transplantation AutologousDisease-Free SurvivalAntibodies Monoclonal Murine-DerivedAutologous stem-cell transplantationhemic and lymphatic diseasesInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansProspective StudiesCD20Salvage TherapyTransplantationPeripheral Blood Stem Cell Transplantationbiologybusiness.industryBone Marrow PurgingRemission InductionAntibodies MonoclonalHematologyMiddle AgedNeoplastic Cells CirculatingHematopoietic Stem Cell MobilizationSurgeryHematopoiesisTransplantationRegimenImmune Systembiology.proteinRituximabFemaleVirus ActivationStem cellbusinessRituximabmedicine.drugBone marrow transplantation
researchProduct

Diferenças na ativação muscular entre a realização de flexões com apoio fixo e com um sistema de suspensão unilateral em forma de V em diferentes alt…

2014

This study was designed to analyze upper extremity and core muscle activation performing push-ups under different stability conditions and body positions. Trained university male students (n= 29) performed 3 push-ups each under stable conditions and using suspension device (AirFit Trainer ProTM) with their hands at 2 different heights (i.e., 10 and 65 cm). Push-up speed was controlled using a metronome and the testing order was randomized. The average amplitudes of the electromyographic root mean square of the Triceps Brachii, Upper Trapezius, Anterior Deltoid, Clavicular Pectoralis, Rectus Abdominis, Rectus Femoris, Lumbar Erector Spinae and Gluteus Maximus were recorded and normalized to …

OrthodonticsCore (anatomy)business.industryPhysical Therapy Sports Therapy and RehabilitationMuscle activationMetronomeIsometric exerciseAnatomylaw.inventionLumbarPush-uplawExercise intensityMedicineOrthopedics and Sports MedicinebusinessSuspension (vehicle)Motricidade
researchProduct

Understanding the role of osteoarthrosis on electromyographic activity of masticatory muscles and quality of life

2019

Background Osteoarthrosis is a severe, evolutionary, chronic, and limiting disease that influences on quality of life, as it affects synovial joints and promoted degradation of hyaline articular cartilage. We sought to determine if electromyographic activity of the masticatory muscles and quality of life are negatively impacted by osteoarthrosis. Material and Methods A sample of 72 participants between 40 and 70 years old diagnosed with osteoarthrosis were selected. Forty-eight participants met the inclusion criteria of this study and were divided into two distinct groups: with osteoarthrosis (n=24) and without osteoarthrosis (n=24). Electromyographic activity of the masseter and temporalis…

OrthodonticsOral Medicine and Pathologybusiness.industryResearchSignificant differenceMuscle activation:CIENCIAS MÉDICAS [UNESCO]Temporal muscleMasticatory forceMasseter muscleQuality of lifeUNESCO::CIENCIAS MÉDICASLateralityMedicinebusinessGeneral DentistryHyalineJournal of Clinical and Experimental Dentistry
researchProduct

Muscle activation during push-ups performed under stable and unstable conditions

2015

Background/Objective: The purpose of this study was to analyze muscle activation when performing push-ups under different stability conditions. Methods: Physically fit young male university students (N = 30) performed five push-ups under stable conditions (on the floor) and using four unstable devices (wobble board, stability disc, fitness dome, and the TRX Suspension Trainer). The push-up speed was controlled using a metronome, and the testing order was randomized. The average amplitudes of the electromyographic (EMG) root mean square of the anterior deltoid (DELT), serratus anterior (SERRA), lumbar multifidus (LUMB), and rectus femoris (FEM) were recorded. The electromyographic signals we…

Orthodonticslcsh:SportsCore (anatomy)medicine.medical_specialtyPublic Health Environmental and Occupational HealthPharmaceutical ScienceInstabilityPharmacology (nursing)Physical Therapy Sports Therapy and RehabilitationMuscle activationIsometric exerciseMetronomelaw.inventionlcsh:GV557-1198.995LumbarEMGPush-uplawAnterior deltoidPhysical therapymedicineOriginal ArticleCoreYoung maleMathematicsJournal of Exercise Science & Fitness
researchProduct