Search results for " ASSOCIATION"
showing 10 items of 996 documents
Sustainability of interlocked fishing district -management concept for commercial fishing in Finnish lake fishery
2012
Genome-Wide Inhibition of Pro-atherogenic Gene Expression by Multi-STAT Targeting Compounds as a Novel Treatment Strategy of CVDs.
2018
Cardiovascular diseases (CVDs), including atherosclerosis, are globally the leading cause of death. Key factors contributing to onset and progression of atherosclerosis include the pro-inflammatory cytokines Interferon (IFN)a and IFN? and the Pattern Recognition Receptor (PRR) Toll-like receptor 4 (TLR4). Together, they trigger activation of Signal Transducer and Activator of Transcription (STAT)s. Searches for compounds targeting the pTyr-SH2 interaction area of STAT3, yielded many small molecules, including STATTIC and STX-0119. However, many of these inhibitors do not seem STAT3-specific. We hypothesized that multi-STAT-inhibitors that simultaneously block STAT1, STAT2, and STAT3 activit…
A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
2017
PubMed ID: 29047407
Survey of Italian Pediatricians on awareness, experiences and beliefs regarding direct-to-consumer genetic testing in minors
2022

 Background: Our study wanted to assess Italian pediatricians’ awareness, experience and beliefs regarding directto-consumer (DTC) genetic tests (GT) in minors, with a focus on those for predisposition to complex disease, lyfestyle, athletic ability and other inborn talents.
 Methods: A 28-item questionnaire was administered through the SurveyMonkey® web platform to the 9,086 members of the Italian Society of Pediatrics for which a valid email address was available. The survey was opened from April through November 2017. Statistical analyses were performed using the Graphpad software package.
 Results: 36.2% of the 442 respondents were aware of DTC-GT, but only 23.1% of them…
Sport as a channel for cultural identity - an examination ofamateur and professional activities : a case study of the Gaelic Athletic Association (GA…
2011
Gaelic Athletic Association (GAA) sports are under the threat of global and more commercially viable sports. This thesis examines the relationship between the GAA and the communities it is involved with. The research has shown a research gap relating to the significance of the GAA in the lives of Irish people, while also examining this organisation through amateur and professional perspectives throughout this research. The impact of this study is of a significant importance in the relationship that exists between Irish people and the GAA. The main research task evaluates the relationship between the GAA as an organisation and the people who participate in the sports. The method of research …
Marsala Wine and Porto Wine, two Important Stories and two Great Wines in Comparison. The Current Market Situation and Opportunities
2012
Introduction Marsala wine is the oldest of the Sicilian wines and it takes its name from the little town where it is produced. It is one of the most famous fortified wines in the world thanks to its organoleptic qualities and its incredible versatility. Despite its ancient origin and its fame, which led this wine to be known all over the world, Marsala wine is for several years in a decline phase. Porto wine, has always been a true symbol of Portugal, is also very famous worldwide for centuries, it is obtained from different varieties of grapes grown in the Douro Valley and then it is aged in wooden barrels at the cellars of the Oporto City where it was then shipped to be exported all over …
Victims of Racket: Entrepreneurs and Traders Dealing with Cosa Nostra, Ndrangheta, and Camorra
2015
This work proposes research on a still unexplored psychical world: thoughts, emotions, and real events experienced by racket victims of the three largest criminal organizations of the South of Italy: Mafia, Camorra, and Ndrangheta. The purpose is to understand the multifaceted psycho-anthropological and social issues criminal organizations have settled on, and particularly which psycho-relational dynamics and sociocultural codes come into play in the complex and controversial relationship between victim and criminal system, between victim and support systems. With entrepreneurs and tradesmen victims of organized crime, we have analyzed lived experiences - in particular fear - and psychologi…
Longitudinal Associations of First-grade Teaching with Reading in Early Primary School
2019
The present study examined the longitudinal associations between first-grade teaching practices and children's reading skills development from Grade 1 to Grade 3. Using the Early Childhood Classroom Observation Measure (ECCOM), the teaching practices of 32 Finnish teachers were observed in Grade 1. Students' (N = 359) word recognition and sentence reading skills were assessed yearly from Grade 1 to Grade 3. The person-oriented analysis identified three profiles of teaching practices in Grade 1: child-centred teaching style, teacher-directed teaching style, and a mixed child-centred and teacher-directed teaching style. Furthermore, the results showed that children whose Grade 1 teachers used…
The definition, screening, and treatment of postpartum anemia: A systematic review of guidelines.
2020
Background: Postpartum anemia can negatively affect maternal health and interfere with early parenting. Thus, it is important to have clear, evidence-informed recommendations on its diagnosis and treatment. Objective: To compare global recommendations regarding the appropriate management of postpartum anemia and to highlight similarities and differences. Methods: Systematic searches were conducted in the databases PubMed, CINAHL, LILACS, TRIP database, and Scopus, and in the websites of health institutions and scientific societies. Search terms were related to anemia and the postpartum period. Two hundred and eighty papers were identified; the full texts of 30 sets of guidelines were review…
Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis
2012
Autosomal recessive renal tubular dysgenesis (RTD) is a severe disorder of renal tubular development characterized by early onset and persistent fetal anuria leading to oligohydramnios and the Potter sequence, associated with skull ossification defects. Early death occurs in most cases from anuria, pulmonary hypoplasia, and refractory arterial hypotension. The disease is linked to mutations in the genes encoding several components of the renin-angiotensin system (RAS): AGT (angiotensinogen), REN (renin), ACE (angiotensin-converting enzyme), and AGTR1 (angiotensin II receptor type 1). Here, we review the series of 54 distinct mutations identified in 48 unrelated families. Most of them are no…