Search results for " Action"

showing 10 items of 3633 documents

A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia

2016

Trigeminal neuralgia (TN) is a form of neuropathic pain that affects the fifth cranial nerve, the most widely distributed nerve in the head. Although TN has been associated with a variety of pathological conditions, neurovascular compression on the trigeminal nerve, as it exits the brain stem, is the most frequent reported cause. This compression provides a progressive demyelination of the nerve and a subsequent aberrant neural transmission. Although several studies have clarified some physiopathological mechanisms underlying TN, the molecular basis remains vague. Very recently the substitution of methionine 136 by valine (MET126Val) in sodium channel Nav1.6 in a case study of typical TN ha…

trigeminal ganglionlcsh:Biochemistry03 medical and health sciencesTrigeminal ganglion0302 clinical medicineaction potentialTrigeminal neuralgianeurovascualr compressionGeneticsmedicinelcsh:QD415-436Molecular BiologyPathologicalTrigeminal neuralgia; action potential; molecular mechanism; neurovascualr compression; trigeminal ganglionGenetics (clinical)Trigeminal nervebusiness.industrySodium channellcsh:RM1-950medicine.diseasePathophysiologylcsh:Therapeutics. Pharmacology030220 oncology & carcinogenesisAnesthesiaNeuropathic painMolecular MedicineBrainstemmolecular mechanismbusinessNeuroscience030217 neurology & neurosurgeryTrigeminal neuralgiaResearch Article
researchProduct

In-depth characterization of denitrifier communities across different soil ecosystems in the tundra

2022

Abstract Background In contrast to earlier assumptions, there is now mounting evidence for the role of tundra soils as important sources of the greenhouse gas nitrous oxide (N2O). However, the microorganisms involved in the cycling of N2O in this system remain largely uncharacterized. Since tundra soils are variable sources and sinks of N2O, we aimed at investigating differences in community structure across different soil ecosystems in the tundra. Results We analysed 1.4 Tb of metagenomic data from soils in northern Finland covering a range of ecosystems from dry upland soils to water-logged fens and obtained 796 manually binned and curated metagenome-assembled genomes (MAGs). We then sear…

tundraDenitrificationMicroorganismDenitrification pathwayBiomeDIVERSITYApplied Microbiology and BiotechnologyCARBONCHLOROFLEXIMULTIPLE SEQUENCE ALIGNMENTArctictyppitypen kiertoNITROUS-OXIDE REDUCTASEgenome-resolved metagenomics11832 Microbiology and virology2. Zero hungermaaperäarktinen alue0303 health sciencesdenitrificationnitrous oxideMICROBIAL COMMUNITYEcologygenomiikkadityppioksidinitraatitkasvihuonekaasutRIBOSOMAL-RNAdenitrifikaatioarctic regionN2O EMISSIONSBiologyMicrobiologyACIDOBACTERIAPERMAFROST03 medical and health sciencesDenitrifying bacteriasoil microbiomeGeneticsarcticGenome-resolved metagenomics030304 developmental biologymetagenomics030306 microbiology15. Life on landTundraekosysteemit (ekologia)mikrobisto13. Climate actionMetagenomicsSoil water
researchProduct

Lege agere pro tutela

2009

Il lavoro propone una nuova interpretazione dell'ipotesi derogatoria ai divieti di lege agere alieno nomine coincidente con il lege agere pro tutela citato in I. 4.10. Contrariamente alle opinioni precedentemente proposte in dottrina, si dimostra come l'agere pro tutela coincidesse con l'agere del tutor ad litem nei casi di oblatio litis ovvero, anteriormente al I sec. d.C., nelle ipotesi di infantia del pupillo o di assenza del pupillo o della mulier.

tutor ad litem.lege agere pro tutelaSettore IUS/18 - Diritto Romano E Diritti Dell'Antichita'legis actioneagere alieno nomine
researchProduct

Ultra-High Energy Neutrinos at the Pierre Auger Observatory

2013

The observation of ultrahigh energy neutrinos (UHE nu s) has become a priority in experimental astroparticle physics. UHE nu s can be detected with a variety of techniques. In particular, neutrinos can interact in the atmosphere (downward-going nu) or in the Earth crust (Earth-skimming nu), producing air showers that can be observed with arrays of detectors at the ground. With the surface detector array of the Pierre Auger Observatory we can detect these types of cascades. The distinguishing signature for neutrino events is the presence of very inclined showers produced close to the ground (i.e., after having traversed a large amount of atmosphere). In this work we review the procedure and …

ultra high energy neutrino[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]Physics::Instrumentation and DetectorsCiencias FísicasAstronomyFluxAstrophysics7. Clean energy01 natural sciencesAltas energíasAuger//purl.org/becyt/ford/1 [https]surface [detector]ObservatoryneutriniCosmic-rayscosmic rayHigh Energy Astrophysical Phenomena (astro-ph.HE)PhysicsCascada atmosférica extensaOBSERVATÓRIOS[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]PhysicsSettore FIS/01 - Fisica SperimentaleAstrophysics::Instrumentation and Methods for Astrophysicsneutrino; Augerlcsh:QC1-999AugercascadeUHE [neutrino]observatoryPhysics::Space PhysicsComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFísica nuclearultra high energy neutrinosNeutrinoAstrophysics - High Energy Astrophysical PhenomenaCIENCIAS NATURALES Y EXACTASsignatureTAU-NEUTRINOSatmosphere [showers]FLUXNuclear and High Energy Physics[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Article SubjectairAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesCosmic rayFísica de Partículas y CamposLIMITPartícules (Física nuclear)Ultra high energy cosmic rayAtmosphere[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]Air-showersSEARCHNeutrino0103 physical sciencesddc:530010306 general physicsAstrophysiqueCiencias ExactasPierre Auger ObservatoryAstroparticle physicsSPECTRUM010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyFísicaUltra high energy cosmic raystelescopes//purl.org/becyt/ford/1.3 [https]Ultrahigh Energyflux13. Climate actionenergy [neutrino]Pierre AugerExperimental High Energy PhysicsARRAYHigh Energy Physics::ExperimentAstroparticle physicslcsh:Physics
researchProduct

Experimental Constraints on the Deep Magma Feeding System at StromboliVolcano, Italy

2009

International audience; New experiments have been performed on a high-K basalt (PST-9) from Stromboli volcano, Italy, to constrain the physical conditions of golden pumice magmas at their storage level and discuss their petrogenesis. Fluid-present, H2O- and CO2-bearing, near-liquidus experiments were performed at 11508C between 100 and 400MPa and under oxidizing conditions. Glasses were analyzed by Fourier transform IR spectroscopy and their H2O and CO2 concentrations compared with those in glass inclusions.Most glass inclusions cluster near the 200MPa isobar, suggesting entrapment at a depth of ~8 km. Golden pumice magmas have viscosities of 7.9 Pa s and densities of 2.48-2.57 g/cm3. Compo…

ultra-calcic melts010504 meteorology & atmospheric sciences[SDE.MCG]Environmental Sciences/Global ChangesMineralogyLiquidus010502 geochemistry & geophysics01 natural sciencesphysical propertiesGeochemistry and PetrologyPumiceexperimental petrology[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/VolcanologyStromboli0105 earth and related environmental sciencesMelt inclusionsPetrogenesisBasaltgeographygeography.geographical_feature_categorygolden pumiceSettore GEO/07 - Petrologia E PetrografiaGeophysicsVolcano13. Climate actionMagmaexperimental petrology Stromboli yellow pumicePrimitive mantlemagma storageGeology
researchProduct

Ultra-high temperature metamorphism recorded in Fe-rich olivine-bearing migmatite from the Khondalite Belt, North China Craton

2018

International audience; We document the first occurrence of Fe‐rich olivine‐bearing migmatitic metapelite in the Khondalite Belt, North China Craton. Petrological analyses revealed two exotic assemblages of orthopyroxene+spinel+olivine and orthopyroxene+spinel+cordierite. Phase relation modelling suggests that these assemblages are diagnostic of ultra‐high temperature (UHT) metamorphism in the Fe‐rich system, with temperatures from 1,000 to 1,050°C at 0.6 GPa. U–Th–Pb SIMS analyses on zircon reveal a similar age of c. 1.92 Ga for the olivine‐bearing migmatite and an adjacent gabbronoritic intrusion that is therefore identified as the heat source for the UHT metamorphism. These results, coup…

ultra-high temperature metamorphism010504 meteorology & atmospheric sciencesGeochemistry[SDU.STU.PE]Sciences of the Universe [physics]/Earth Sciences/PetrographyMetamorphismengineering.material010502 geochemistry & geophysics01 natural sciencesNorth China CratonKhondalite BeltGeochemistry and PetrologymigmatitesPetrology0105 earth and related environmental sciences[ SDU.STU.PE ] Sciences of the Universe [physics]/Earth Sciences/Petrographygeographygeography.geographical_feature_categoryOlivineUltra-high-temperature metamorphismGeologymetamorphic olivineMigmatiteGranuliteCraton13. Climate actionengineeringKhondaliteMaficGeology
researchProduct

The Promise and Deception of Participation in Welfare Services for Unemployed Young People

2018

This study examined the role of welfare services in the participative citizenship of young people under 30 years of age outside the labour market. Thematic content analysis of the government’s white papers regarding participation policies, as well as participatory action research projects in two Finnish towns, were used to identify factors that enable or hinder participation for this group of service users. The paradigm of participation was critically examined with reference to the theoretical framework of Max Horkheimer and Theodor Adorno’s “dialectic of Enlightenment”, which proposes the parallel existence of the promise and the deception of Enlightenment. The results indicated that user …

unemploymentdialectic of Enlightenmentmedia_common.quotation_subjectParticipatory action researchtyömarkkinatyoung peoplelcsh:Social SciencesosallistaminennuoretMedia TechnologyDemocratizationSociologymedia_commonosallistuminenGovernmentSocial workbusiness.industrywelfare serviceshyvinvointipalvelutPublic relationsDeceptiontyöttömyysparadigm of participationlcsh:HWorkfareWorkforceThematic analysisbusinessCritical Social Work
researchProduct

Alteration-Induced Volcano Instability at La Soufrière de Guadeloupe (Eastern Caribbean)

2021

International audience; Volcanoes are unstable structures that deform laterally and frequently experience mass wasting events. Hydrothermal alteration is often invoked as a mechanism that contributes significantly to volcano instability. We present a study that combines laboratory experiments, geophysical data, and large-scale numerical modeling to better understand the influence of alteration on volcano stability, using La Soufrière de Guadeloupe (Eastern Caribbean) as a case study. Laboratory experiments on variably altered (advanced argillic alteration) blocks show that uniaxial compressive strength, Young's modulus, and cohesion decrease as a function of increasing alteration, but that …

upscalingVolcanic hazards010504 meteorology & atmospheric sciencesYoung's modulusMass wasting010502 geochemistry & geophysics01 natural sciencesInstabilityHydrothermal circulationGeochemistry and PetrologyFriction angleEarth and Planetary Sciences (miscellaneous)Cohesion (geology)[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/VolcanologyArgillic alterationPetrologyhydrothermal alterationuniaxial compressive strength0105 earth and related environmental sciencesflank collapsegeographygeography.geographical_feature_categoryGeophysicsVolcano13. Climate actionSpace and Planetary ScienceGeology
researchProduct

On Line Validation Exercise (OLIVE): A Web Based Service for the Validation of Medium Resolution Land Products. Application to FAPAR Products

2014

International audience; The OLIVE (On Line Interactive Validation Exercise) platform is dedicated to the validation of global biophysical products such as LAI (Leaf Area Index) and FAPAR (Fraction of Absorbed Photosynthetically Active Radiation). It was developed under the framework of the CEOS (Committee on Earth Observation Satellites) Land Product Validation (LPV) sub-group. OLIVE has three main objectives: (i) to provide a consistent and centralized information on the definition of the biophysical variables, as well as a description of the main available products and their performances (ii) to provide transparency and traceability by an online validation procedure compliant with the CEO…

validation;LAI;FAPAR;intercomparison;product;CEOSService (systems architecture)Earth observationTraceabilityComputer scienceScienceintercomparison10127 Institute of Evolutionary Biology and Environmental StudiesDocumentationBenchmark (surveying)Web applicationproductFAPARComputingMilieux_MISCELLANEOUSRemote sensingvalidationbusiness.industryQ1900 General Earth and Planetary SciencesLAI13. Climate action[SDE]Environmental Sciences570 Life sciences; biology590 Animals (Zoology)General Earth and Planetary SciencesbusinessHost (network)Quality assuranceCEOSRemote Sensing
researchProduct

Inferring Phytoplankton, Terrestrial Plant and Bacteria Bulk δ¹³C Values from Compound Specific Analyses of Lipids and Fatty Acids.

2015

Stable isotope mixing models in aquatic ecology require δ13C values for food web end members such as phytoplankton and bacteria, however it is rarely possible to measure these directly. Hence there is a critical need for improved methods for estimating the δ13C ratios of phytoplankton, bacteria and terrestrial detritus from within mixed seston. We determined the δ13C values of lipids, phospholipids and biomarker fatty acids and used these to calculate isotopic differences compared to the whole-cell δ13C values for eight phytoplankton classes, five bacterial taxa, and three types of terrestrial organic matter (two trees and one grass). The lipid content was higher amongst the phytoplankton (…

ved/biology.organism_classification_rank.speciesta1172lcsh:MedicineAlgaeaquatic ecologyterrestrial plantsPhytoplanktonTerrestrial plantBotanyMetabolomics14. Life underwaterBiomasslcsh:Sciencevesiekologia2. Zero hungerBiomass (ecology)Carbon IsotopesMultidisciplinaryDetritusbiologyδ13CBacteriaved/biologyStable isotope ratioSestonFatty Acidsfungilcsh:R15. Life on landbiology.organism_classificationLipidsbacteria bulk13. Climate actionEnvironmental chemistryPhytoplanktonphytoplanktonta1181lcsh:QBiomarkersResearch ArticlePLoS ONE
researchProduct