Search results for " Active"
showing 10 items of 533 documents
An innovative respirometric method to assess the autotrophic active fraction: Application to an alternate oxic-anoxic MBR pilot plant
2016
An innovative respirometric method was applied to evaluate the autotrophic active fraction in an alternate anoxic/oxic membrane bioreactor (MBR) pilot plant. The alternate cycle (AC) produces a complex microbiological environment that allows the development of both autotrophic and heterotrophic species in one reactor. The present study aimed to evaluate autotrophic and heterotrophic active fractions and highlight the effect of different aeration/non aeration ratios in a AC-MBR pilot plant using respirometry. The results outlined that the autotrophic active fraction values were consistent with the nitrification efficiency and FISH analyses, which suggests its usefulness for estimating the ni…
Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function
2001
The heterodimeric peptide transporter associated with antigen processing (TAP) consisting of the subunits TAP1 and TAP2 mediates the transport of cytosolic peptides into the lumen of the endoplasmic reticulum (ER). In order to accurately define domains required for peptide transporter function, a molecular approach based on the construction of a panel of human TAP1 mutants and their expression in TAP1(-/-) cells was employed. The characteristics and biological activity of the various TAP1 mutants were determined, and compared to that of wild-type TAP1 and TAP1(-/-) control cells. All mutant TAP1 proteins were localized in the ER and were capable of forming complexes with the TAP2 subunit. H…
TOWARDS A LIVING-ORIENTED APPROACH TO URBAN DESIGN BY COSMOPOLITAN RISK COMMUNITIES
2021
At a defining moment for the future of life on Earth, active citizenship and informed communities play a decisive role in sensitising stakeholders to issues and influencing their decisions via physical and digital platforms. Anthropogenic climate change generates risks, causes migrations, expands inequalities, and mobilises people: these challenges question both the relationship of coexistence between different cultures and that between humans and other living species, such as animals, insects, and plants. If inhabiting cosmopolitan cities means living in and sharing a plural habitat, it is of utmost importance that we gather our collective expertise and rethink cities as welcoming spaces f…
Childhood Sports Participation Is Associated With Health-Related Quality of Life in Young Men: A Retrospective Cross-Sectional Study
2021
The aim of the study was to examine whether sports participation (SP), engagement in competitive sports (CS) and the type of sport undertaken at the age of 12 are associated with the physical and the mental components of health-related quality of life (HRQoL) in young adulthood. The data were collected using questionnaires prior to a compulsory military refresher training course in Finland. The sample consisted of 784 men (mean age 26 years). HRQoL was measured with RAND 36 and childhood sports participation with a series of questions. Data were analysed with logistic regression. Higher frequency of SP, participation in district level CS, performing team, endurance or extreme sports and pla…
Promoting active ageing through a physical exercise program aimed at reducing frailty and risk of falling among older adults
2017
Introduction: Risk of falling and frailty have been revealed as the most important conditions causing dependency among older people [1]. Older adults taking physical activity regularly can benefit of a proper maintenance of muscle strength and mass, which helps to retain function and independence, and to prevent falls and other injuries [2]. Concretely, the effectiveness of balance and strength training programs on the reduction of falls [3] and frailty [4] has been sufficiently proved.Theory/Methods: This study was conducted to evaluate the effect of an intervention based on a physical exercise program addressed at 65+ people suffering from risk of falling and frailty, and ultimately aimed…
Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): a DEDIPAC-study
2016
International audience; Background: A large proportion of European children, adults and older adults do not engage in sufficient physical activity ( PA). Understanding individual and contextual factors associated with PA behaviours is essential for the identification and implementation of effective preventative environments, policies, and programmes that can promote an active lifestyle across life course and can potentially improve health. The current paper intends to provide 1) a multi-disciplinary, Pan-European and life course view of key determinants of PA behaviours and 2) a proposal of how these factors may cluster. Methods: After gathering a list of 183 potential PA behaviours-associa…
Protein, creatine and dieting supplements among adolescents: Use and associations with eating disorder risk factors, exercise- and sports participati…
2021
Objective: This study aimed to estimate the number of weekly users of protein, creatine, and dieting supplements and to explore whether weekly use was related to eating disorder (ED) risk factors, exercise, sports participation, and immigrant status.Methods: In total, 629 and 1,060 high school boys and girls, respectively, self-reported weekly frequency of protein, creatine, and dieting supplement use, and weight and shape concerns, appearance internalization and pressure, self-esteem, mental distress, physical activity level, exercise context, and the type and weekly frequency of sport played. Multiple hierarchical regression analyses were performed to investigate explanatory factors for s…
Intercomparison and quality assessment of MERIS, MODIS and SEVIRI FAPAR products over the Iberian Peninsula
2013
Abstract The fraction of absorbed photosynthetically active radiation (FAPAR) is a key variable in productivity and carbon cycle models. The variety of available FAPAR satellite products from different space agencies leads to the necessity of assessing the existing differences between them before using into models. Discrepancies of four FAPAR products derived from MODIS, SEVIRI and MERIS (TOAVEG and MGVI algorithms), covering the Iberian Peninsula from July 2006 to June 2007 are here analyzed. The assessment is based on an intercomparison involving the spatial and temporal consistency between products and a statistical analysis across land cover types. In general, significant differences ar…
A new actor involved in hypothalamic glucose detection : the Transient Receptor Potential Canonical (TRPC) channels
2015
Hyperglycemia is detected and integrated by the mediobasal hypothalamus (MBH) which, in turn, inhibits food intake and triggers insulin secretion. The MBH houses specialized glucose-sensitive (GS) neurons, which directly or indirectly modulate their electrical activity in response to changes in glucose level. In a first study, we hypothesized that indirect detection of glucose by MBH GS neurons involves the secretion of endozepine by astrocytes, a gliotransmitter known to inhibit food intake in response to hyperglycemia. The present work shows that endozepines selectively activate anorexigenic MBH pro-opiomelanotortine (POMC) neurons. In the second study, we show that the direct detection o…
GM-CSF restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro.
2003
Abstract Infection remains the major complication of immunosuppressive therapy in organ transplantation. Therefore, reconstitution of the innate immunity against infections, without activation of the adaptive immune responses, to prevent graft rejection is a clinically desirable status in transplant recipients. We found that GM-CSF restored TNF mRNA and protein expression without inducing IL-2 production and T cell proliferation in glucocorticoid-immunosuppressed blood from either healthy donors or liver transplant patients. Gene array experiments indicated that GM-CSF selectively restored a variety of dexamethasone-suppressed, LPS-inducible genes relevant for innate immunity. A possible ex…