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showing 10 items of 533 documents
Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications
2015
Mitochondrial function and specifically its implication in cellular redox/oxidative balance is fundamental in controlling the life and death of cells, and has been implicated in a wide range of human pathologies. In this context, mitochondrial therapeutics, particularly those involving mitochondria-targeted antioxidants, have attracted increasing interest as potentially effective therapies for several human diseases. For the past 10 years, great progress has been made in the development and functional testing of molecules that specifically target mitochondria, and there has been special focus on compounds with antioxidant properties. In this review, we will discuss several such strategies, …
Green sulphur bacteria as a component of the photosynthetic plankton community in small dimictic humic lakes with an anoxic hypolimnion
2013
High bacteriochlorophyll (BChl) concentrations in the anoxic water layers of some humic lakes have indicated that green sulphur bacteria (GSB) may be ecologically significant. The abundance and spatial distribution of GSB were therefore addressed in 13 small humic lakes using fragment analysis and sequencing of PCR-amplified 16S rRNA genes. GSB were detected from lakes where the photosynthetically active radiation was at least 1.1 µE m �2 s �1 at the oxic� anoxic boundary layer. In these lakes, 13 to 42% of the 16S rRNA gene sequences of the anoxic water column were assigned to GSB. The spatial distribution of GSB was tightly correlated with the spectrophotometrically measured BChl concentr…
LeMMINGs III. The e-MERLIN legacy survey of the Palomar sample: exploring the origin of nuclear radio emission in active and inactive galaxies throug…
2021
Full list of authors: Baldi, R. D.; Williams, D. R. A.; Beswick, R. J.; McHardy, I.; Dullo, B. T.; Knapen, J. H.; Zanisi, L.; Argo, M. K.; Aalto, S.; Alberdi, A.; Baan, W. A.; Bendo, G. J.; Fenech, D. M.; Green, D. A.; Klöckner, H. -R.; Körding, E.; Maccarone, T. J.; Marcaide, J. M.; Mutie, I.; Panessa, F.; Pérez-Torres, M. A.; Romero-Cañizales, C.; Saikia, D. J.; Saikia, P.; Shankar, F.; Spencer, R. E.; Stevens, I. R.; Uttley, P.; Brinks, E.; Corbel, S.; Martí-Vidal, I.; Mundell, C. G.; Pahari, M.; Ward, M. J.
Radio and gamma-ray properties of extragalactic jets from the TANAMI sample
2016
Using high-resolution radio imaging with VLBI techniques, the TANAMI program has been observing the parsec-scale radio jets of southern (declination south of -30{\deg}) gamma-ray bright AGN simultaneously with Fermi/LAT monitoring of their gamma-ray emission. We present the radio and gamma-ray properties of the TANAMI sources based on one year of contemporaneous TANAMI and Fermi/LAT data. A large fraction (72%) of the TANAMI sample can be associated with bright gamma-ray sources for this time range. Association rates differ for different optical classes with all BL Lacs, 76% of quasars and just 17% of galaxies detected by the LAT. Upper limits were established on the gamma-ray flux from TAN…
A Highly Magnetized Twin-Jet Base Pinpoints a Supermassive Black Hole
2016
Supermassive black holes (SMBH) are essential for the production of jets in radio-loud active galactic nuclei (AGN). Theoretical models based on Blandford & Znajek extract the rotational energy from a Kerr black hole, which could be the case for NGC1052, to launch these jets. This requires magnetic fields of the order of $10^3\,$G to $10^4\,$G. We imaged the vicinity of the SMBH of the AGN NGC1052 with the Global Millimetre VLBI Array and found a bright and compact central feature, smaller than 1.9 light days (100 Schwarzschild radii) in radius. Interpreting this as a blend of the unresolved jet bases, we derive the magnetic field at 1 Schwarzschild radius to lie between 200 G and ~8000…
Discovery of off-axis jet structure of TeV blazar Mrk 501 with mm-VLBI
2016
Context. High-resolution millimeter wave very-long-baseline interferometry (mm-VLBI) is an ideal tool for probing the structure at the base of extragalactic jets in detail. The TeV blazar Mrk 501 is one of the best targets among BL Lac objects for studying the nature of off-axis jet structures because it shows different jet position angles at different scales. Aims. The aim of this study is to investigate the properties of the off-axis jet structure through high-resolution mm-VLBI images at the jet base and physical parameters such as kinematics, flux densities, and spectral indices. Methods. We performed Very Long Baseline Array (VLBA) observations over six epochs from 2012 February to 201…
ANTARES constrains a blazar origin of two IceCube PeV neutrino events
2015
Abstract Context. The source(s) of the neutrino excess reported by the IceCube Collaboration is unknown. The TANAMI Collaboration recently reported on the multiwavelength emission of six bright, variable blazars which are positionally coincident with two of the most energetic IceCube events. Objects like these are prime candidates to be the source of the highest-energy cosmic rays, and thus of associated neutrino emission. Aims. We present an analysis of neutrino emission from the six blazars using observations with the ANTARES neutrino telescope. Methods. The standard methods of the ANTARES candidate list search are applied to six years of data to search for an excess of muons and hence th…
Multifrequency Studies of the Peculiar Quasar 4C +21.35 during the 2010 Flaring Activity
2014
著者人数: 290名
An Indication of Anisotropy in Arrival Directions of Ultra-high-energy Cosmic Rays through Comparison to the Flux Pattern of Extragalactic Gamma-Ray …
2018
A new analysis of the dataset from the Pierre Auger Observatory provides evidence for anisotropy in the arrival directions of ultra-high-energy cosmic rays on an intermediate angular scale, which is indicative of excess arrivals from strong, nearby sources. The data consist of 5514 events above 20 EeV with zenith angles up to 80 deg recorded before 2017 April 30. Sky models have been created for two distinct populations of extragalactic gamma-ray emitters: active galactic nuclei from the second catalog of hard Fermi-LAT sources (2FHL) and starburst galaxies from a sample that was examined with Fermi-LAT. Flux-limited samples, which include all types of galaxies from the Swift-BAT and 2MASS …
The role of Kelvin-Helmholtz instability in the internal structure of relativistic outflows. The case of the jet in 3C 273
2006
Relativistic outflows represent one of the best-suited tools to probe the physics of AGN. Numerical modelling of internal structure of the relativistic outflows on parsec scales provides important clues about the conditions and dynamics of the material in the immediate vicinity of the central black holes in AGN. We investigate possible causes of the structural patterns and regularities observed in the parsec-scale jet of the well-known quasar 3C 273. We present here the results from a 3D relativistic hydrodynamics numerical simulation based on the parameters given for the jet by Lobanov & Zensus (2001), and one in which the effects of jet precession and the injection of discrete compone…