Search results for " Aging"
showing 10 items of 584 documents
Healthy Aging and Sentence Production: Disrupted Lexical Access in the Context of Intact Syntactic Planning.
2020
AbstractHealthy ageing does not affect all features of language processing equally. In this study, we investigated the effects of ageing on different processes involved in fluent sentence production, a complex task that requires the successful execution and coordination of multiple processes. In Experiment 1, we investigated age-related effects on the speed of syntax selection using a syntactic priming paradigm. Both young and older adults produced target sentences quicker following syntactically related primes compared to unrelated primes, indicating that syntactic facilitation effects are preserved with age. In Experiment 2, we investigated age-related effects in syntactic planning and le…
Portret staruszki w rosyjskiej memuarystyce kobiecej XIX wieku
2017
Portrayal of an old woman in the memoirs written bythe nineteenth century Russian womenIn the present article has been analysed portrayals of older women which appear in the memoirs of the nineteenth century Russian women writers. J. Sushkova, A. Kern and A. Smirnova-Rosset in their memoirs most often depict remarkable family members such as grandmothers and aunts, family friends. They focus on the analysis of their personalities, spiritual values and kind-heartedness rather than their physical appearance and signs of physical aging. Among the old ladies portrayed in the memoirs we encounter pious women, wise, experienced, understanding and hospitable women as well as overbearing women or …
Stem cells, cancer stem-like cells, and natural products.
2012
Somatic stem cells can be found in many rapidly regenerating tissues, e.g., the skin, gastrointestinal mucosa, and hematopoietic system, but are also present at low numbers in non-regenerative organs such as the heart and brain. In these organs, somatic stem cells aid in normal tissue homeostasis and repair after injury as well as self-renewal and the generation of specific progenitor cells during differentiation. Cancer stem-like cells are a small subpopulation of self-renewing cells that are able to proliferate upon appropriate stimulation and differentiate into heterogeneous lineages in tumors. Modulation of the behavior of normal tissue stem cells and cancer stem-like cells is an emergi…
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders
2010
In recent years there has been a growing interest, supported by a large number of experimental and epidemiological studies, in the beneficial effects of some commonly used food-derived products in preventing various age-related pathologic conditions, ranging from cancer to neurodegenerative diseases. Spices and herbs often contain active phenolic substances endowed with potent antioxidative and chemopreventive properties. Curcumin is a phytochemical compound extracted from the rhizome of Curcuma Longa. It is the pigment responsible for the characteristic yellow color of Indian curry. Data from our and other laboratories demonstrated that curcumin, as well as some other polyphenols, strongly…
The Impact of Population Ageing and Social Stratification: The Case of Latvia
2019
Population ageing and social stratification is widely assumed to have detrimental effects on the economy yet there is little empirical evidence about the magnitude of its effects. The aim of this article is to investigate the relationships between population ageing and social stratification and the state of economy of a small and post-transition economy. We are looking for these relationships and their strength of influence; at what time after shocking these variables reach their original levels. We apply standard Granger (non-) causality tests, VAR (Vector Auto-Regressive), IRF (Impulse Response Function) and the prediction error variance analysis by using quarterly data from 2000 to 2018.…
Depopulation in the Baltic states
2011
Šiame straispnyje nagrinėjami pagrindiniai Baltijos šalyse vykstančių demografinių procesų bruožai. Atkūrus nepriklausomybę Estijoje, Latvijoje ir Lietuvoje išryškėjo gyventojų skaičiaus mažėjimo tendencija, kurią nulėmė neigiama natūrali gyventojų kaita ir neigiama neto tarptautinė migracija (išvykusiųjų skaičius viršija atvykusiųjų skaičių). Kartų kaitos neužtikrinantis gimstamumo lygis, santykinai aukštas mirtingumo lygis (ypač vyrų), intensyvi emigracija ir gyventojų senėjimas stebimi visose Baltijos šalyse. Šios nepalankios tendencijos ypač pasireiškė šalims įstojus į Europos Sąjungą 2004 m. Nuo 1990 m. Latvija ir Lietuva pasižymi vienais iš didžiausių depopuliacijos tempų Europoje. De…
Low in vivo brain glucose consumption and high oxidative stress in accelerated aging
2009
AbstractThe validity of the free radical theory of aging has been recently questioned. Our aim was to test whether there is oxidative stress in tissues critically involved in accelerated aging (senescence-accelerated mice, SAM) and whether this correlates with lower glucose consumption in vivo and behavioural tests. Positron emission tomography shows that brains of old SAM-prone animals consume less glucose than young ones. Behavioural characteristics, mitochondrial peroxide production, and damage in both the central nervous system and bone marrow stem cells also indicate that SAM-prone animals age faster than SAM-resistant ones. Our results support the role of the free radical theory of ag…
Prevalence and characteristics of prisoners requiring end-of-life care: A prospective national survey
2017
Background: Ensuring adequate end-of-life care for prisoners is a critical issue. In France, data investigating the impact of laws allowing release of seriously ill prisoners are lacking. Aim: To assess the number and characteristics of prisoners requiring palliative care in French prisons. Design: A prospective, national survey collecting data over a 3-month period. Setting/participants: All healthcare units ( n = 190) providing care for prisoners in France. The prison population was 66,698 during the study period. Data collection concerned prisoners requiring end-of-life care, that is, with serious, advanced, progressive, or terminal illness and life expectancy <1 year. Results: Estima…
Anti-Aging Physiological Roles of Aryl Hydrocarbon Receptor and Its Dietary Regulators
2021
The vast majority of the literature on the aryl hydrocarbon receptor is concerned with its functions in xenobiotic detoxification. However, in the course of evolution, this receptor had to have physiological (rather than toxicological) functions. Our aim was to review the aryl hydrocarbon receptor’s role in the physiological functions involved in aging. This study was performed by searching the MEDLINE and Google Academic databases. A total of 34 articles were selected that focused specifically on the aryl hydrocarbon receptor and aging, the aryl hydrocarbon receptor and physiological functions, and the combination of both. This receptor’s main physiological functions (mediated by the modul…
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases
2020
Abstract Adaptogens comprise a category of herbal medicinal and nutritional products promoting adaptability, resilience, and survival of living organisms in stress. The aim of this review was to summarize the growing knowledge about common adaptogenic plants used in various traditional medical systems (TMS) and conventional medicine and to provide a modern rationale for their use in the treatment of stress‐induced and aging‐related disorders. Adaptogens have pharmacologically pleiotropic effects on the neuroendocrine‐immune system, which explain their traditional use for the treatment of a wide range of conditions. They exhibit a biphasic dose‐effect response: at low doses they function as …