Search results for " Alternative"

showing 10 items of 755 documents

The Multi-period Multi-trip Container Drayage Problem with Release and Due Dates

2021

Abstract The Container Drayage Problem (CDP) aims at routing a fleet of trucks, based at a common terminal, to serve customers while minimizing the total travel distance. Each trip starts from and ends at the terminal, and handles a subset of customers. Each customer requires either that a container is picked up or delivered. We introduce a more realistic variant, i.e., the Multi-trip Multi-period CDP with Release and Due Dates (MM-CDP-RDD), in which the planning horizon is composed of several periods (days). On each day, each truck may perform more than one trip respecting the Release and Due Dates (RDD) associated with customer services, corresponding to the first and the last day on whic…

TruckService (business)Routing Multi-trip Vehicle Routing Multi-period Vehicle Routing Combinatorial Benders’ CutsGeneral Computer ScienceOperations researchComputer scienceVehicle routing problem Alternative fuel vehicles Mixed integer linear programming Cutting planes Fueling pump reservationTime horizonManagement Science and Operations ResearchMulti-trip Vehicle RoutingMulti-period Vehicle RoutingSet (abstract data type)Terminal (electronics)Modeling and SimulationContainer (abstract data type)Combinatorial Benders’ CutsSettore MAT/09 - Ricerca OperativaRouting (electronic design automation)Integer programmingRoutingComputers & Operations Research
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Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent a…

2010

Artemisia annua L. (sweet wormwood, qinhao) has traditionally been used in Chinese medicine. The isolation of artemisinin from Artemisia annua and its worldwide accepted application in malaria therapy is one of the showcase success stories of phytomedicine during the past decades. Artemisinin-type compounds are also active towards other protozoal or viral diseases as well as cancer cells in vitro and in vivo. Nowadays, Artemisia annua tea is used as a self-reliant treatment in developing countries. The unsupervised use of Artemisia annua tea has been criticized to foster the development of artemisinin resistance in malaria and cancer due to insufficient artemisinin amounts in the plant as c…

Trypanosoma brucei bruceiArtemisia annuaPharmaceutical ScienceArtemisia annuaPharmacologyHeLachemistry.chemical_compoundPhytomedicineParasitic Sensitivity TestsScopoletinparasitic diseasesDrug DiscoverymedicineHumansArtemisininOligonucleotide Array Sequence AnalysisPharmacologyScopoletinEucalyptolDose-Response Relationship DrugMolecular StructurebiologyPlant Extractsfood and beveragesCyclohexanolsbiology.organism_classificationAntineoplastic Agents PhytogenicTrypanocidal AgentsArtemisininsBioactive compoundEucalyptolComplementary and alternative medicinechemistryDrug Resistance NeoplasmCancer cellMonoterpenesMolecular MedicineDrug Screening Assays AntitumorHeLa Cellsmedicine.drugPhytomedicine
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Análisis del comportamiento de la demanda de turismo rural desde la experiencia de la comarca El Alto Palancia

2004

This study is intended to delve into the tastes and preferences of tourists visiting rural areas in Spain as an alternative to the traditional sun and beach holiday that dominates Spanish tourism. This paper is focused on the demand side of rural tourism; more specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia region, exhibit different behaviours depending on age, gender, incomes and educational background. The homogeneity of behaviour across several categories of tourists was tested in two sets of variables. First, «interest in certain resources associated with rural tourism», focused on natural and architectural resources that sustains the tourist's …

Turismo ruralcomunidad valencianademandaGeography Planning and DevelopmentRural tourismlcsh:G1-922This study is intended to delve into the tastes and preferences of tourists visiting rural areas in Spain as an alternative to the traditional sun and beach holiday that dominates Spanish tourism. This paper is focused on the demand side of rural tourism; more specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia region exhibit different behaviours depending on age gender incomeTurisme ruralemore specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia regionEnvironmental protectionexhibit different behaviours depending on ageRegional sciencegenderdemandehomogénéitéEarth-Surface ProcessesprofileGeography (General)Demand sideperfilregion de Valenciamore specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia region exhibit different behaviours depending on age gender incomeGeographyincomeG1-922Turismo rural; comunidad valenciana; demanda; homogeneidad; perfil; Turisme rurale; region de Valencia; demande; homogénéité; profilehomogeneidadRural areaThis study is intended to delve into the tastes and preferences of tourists visiting rural areas in Spain as an alternative to the traditional sun and beach holiday that dominates Spanish tourism. This paper is focused on the demand side of rural tourismlcsh:Geography (General)Tourism
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Chionaeosides A–D, Triterpene Saponins from Paronychia chionaea

2007

Four new triterpenoid saponins, chionaeosides A-D (1-4) were isolated from the roots of Paronychia chionaea. On the basis of their spectroscopic data, the structures of the new saponins were established as 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--3)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (1), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (2), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranoside (3), and 3-O-alpha-L-arabinopyranosylgypsogenic acid (4).

TurkeyStereochemistrySaponinPharmaceutical ScienceParonychia (plant)CaryophyllaceaePharmacognosyPlant RootsAnalytical ChemistryTriterpenoidTriterpeneDrug DiscoveryTrisaccharidePharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryMolecular MedicineJournal of Natural Products
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Triterpene Glycosides from the Roots of Astragalus flavescens

2007

Six new triterpene saponins, 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (1), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (2), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-beta-D-glucopyranosyl-21-epi-kudzusapogenol A (3), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-beta-D-glucopyranosyl-21-epi-kudzusapogenol A (4), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-alpha-L-arabinopyranosyl-21-epi-kudzus…

TurkeyStereochemistrySaponinPharmaceutical ScienceUronic acidPharmacognosyPlant RootsAnalytical Chemistrychemistry.chemical_compoundTriterpeneDrug DiscoveryTrisaccharideNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideStereoisomerismAstragalus PlantSaponinsbiology.organism_classificationTriterpenesTerpenoidAstragalusComplementary and alternative medicinechemistryMolecular MedicineJournal of Natural Products
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Atkritumu apsaimniekošanas alternatīvu ekonomiskais izvērtējums.

2017

Maģistra darba “Atkritumu apsaimniekošanas alternatīvu ekonomikas izvērtējums” mērķis ir veikt atkritumu apsaimniekošanas alternatīvu ekonomikas izvērtējumu, lai varētu noteikt Latvijai piemērotu un ekonomiski pamatotu atkritumu apsaimniekošanas alternatīvu, kas nodrošinātu Eiropas Savienības direktīvās noteikto mērķu mājsaimniecības atkritumu pārstrādei un apglabāšanas samazināšanas mērķu sasniegšanu 2030.gadā. Izstrādājot maģistra darbu, tika izvērtētas iespējamās metodes atkritumu apsaimniekošanas alternatīvu ekonomikas izvērtējumam. Tika veikta trīs atkritumu apsaimniekošanas alternatīvu ekonomikas izvērtējums, izmantojot izmaksu – ieguvumu analīzi un ekspertu aptauju. Pamatojoties uz v…

Vadībzinātneizmaksu – ieguvumu analīzeatkritumu apsaimniekošanas alternatīvascost – benefit analysiswaste management alternativesatkritumu sadedzināšana
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Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.

2021

AbstractSleep disorders are common among the general population and can generate health problems such as insomnia and anxiety. In addition to standard drugs and psychological interventions, there are different complementary plant-based therapies used to treat insomnia and anxiety. This review aimed to find and examine the most recent research on the use of herbal medicines for treating anxiety and insomnia as compiled from clinical trials, as well as to assess the safety and efficacy of these medicines and to elucidate their possible mechanisms of action. The process entailed a search of PubMed, Scopus, and the Cochrane Library databases from 2010 to 2020. The search terms included “sleep d…

Valerianmedicine.medical_specialtyPopulationPsychological interventionPharmaceutical ScienceCochrane LibraryAnxietyAnalytical Chemistry03 medical and health sciences0302 clinical medicineSleep Initiation and Maintenance DisordersDrug DiscoveryInsomniamedicineHumanseducationPsychiatryPharmacologyeducation.field_of_studySleep disorderPlants Medicinalbiologybusiness.industryOrganic Chemistrybiology.organism_classificationmedicine.diseaseAnxiety DisordersClinical trialComplementary and alternative medicine030220 oncology & carcinogenesisMolecular MedicineAnxietymedicine.symptombusiness030217 neurology & neurosurgeryPhytotherapyPlanta medica
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Le operazioni straordinarie come strumenti per lo sviluppo delle aziende

2006

Valutazione d'azienda metodi tradizionali proposte alternative
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Primi dati sulla coltivazione del fagiolo azuki (Vigna angularis) e del fagiolo indiano (V. radiata) nell'Orto botanico di Palermo

2012

Vigna Orto botanico colture alternative
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Activity investigation of pinostrobin towards herpes simplex virus-1 as determined by atomic force microscopy

2009

In the present study, the antiviral activity of pinostrobin towards herpes simplex virus-1 (HSV-1) was investigated by MTT assay and atomic force microscopy. Pinostrobin can inhibit HSV-1 replication with 50% effective concentration (EC(50)) of 22.71 ± 1.72 μg/ml. MTT assay showed HSV-1 was significantly inhibited when pretreated with pinostrobin, with the inhibition of 85.69 ± 2.59%. Significant changes in morphology and size of HSV-1 were observed by atomic force microscopy (AFM) in response to pinostrobin treatment. AFM topography and phase images showed that with increasing time, the envelope was shedded and damaged, finally leading to virus inactivation. With increasing concentration, …

Virus inactivationPharmaceutical ScienceMice Inbred StrainsHerpesvirus 1 HumanMicrobial Sensitivity TestsMicroscopy Atomic Forcemedicine.disease_causePhase imageMiceIn vivoChlorocebus aethiopsDrug DiscoverymedicineAnimalsMTT assayTreatment effectVero CellsPharmacologyPlant ExtractsChemistryAtomic force microscopyHerpes SimplexVirologyHerpes simplex virusComplementary and alternative medicineFlavanonesBiophysicsVero cellMolecular MedicinePhytotherapyPhytomedicine
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