6533b872fe1ef96bd12d42dc

RESEARCH PRODUCT

Chionaeosides A–D, Triterpene Saponins from Paronychia chionaea

Serdar ŞEnolÖZgen Alankuş ÇAlişkanMarie Aleth Lacaille-duboisTomofumi MiyamotoSibel AvundukErdal Bedir

subject

TurkeyStereochemistrySaponinPharmaceutical ScienceParonychia (plant)CaryophyllaceaePharmacognosyPlant RootsAnalytical ChemistryTriterpenoidTriterpeneDrug DiscoveryTrisaccharidePharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryMolecular Medicine

description

Four new triterpenoid saponins, chionaeosides A-D (1-4) were isolated from the roots of Paronychia chionaea. On the basis of their spectroscopic data, the structures of the new saponins were established as 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--3)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (1), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (2), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranoside (3), and 3-O-alpha-L-arabinopyranosylgypsogenic acid (4).

https://doi.org/10.1021/np0704607