0000000000246172

AUTHOR

Sibel Avunduk

showing 6 related works from this author

Cycloartane Glycosides from Three Species of Astragalus (Fabaceae)

2011

Nine cycloartane-type glycosides were isolated from three species of the genus Astragalus (Fabaceae): From the aerial parts of A. cicer L., two new saponins, cicerosides A and B (1 and 2, resp.), i.e., a tetradesmosidic and tridesmosidic cycloartane-type glycosides besides one known compound, from the roots of A. sempervirensLam., one known saponin, and from the roots of A. ptilodesBoiss. var. cariensisBoiss., five known compounds. Their structures were established mainly by 600-MHz 2D-NMR techniques (1H,1H-COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectroscopy.

chemistry.chemical_classificationbiologyAstragalus speciesOrganic ChemistrySaponinGlycosideFabaceaebiology.organism_classificationBiochemistryCatalysisInorganic ChemistryAstragaluschemistryGenusDrug DiscoveryBotanyPhysical and Theoretical ChemistryTwo-dimensional nuclear magnetic resonance spectroscopyHelvetica Chimica Acta
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Cycloartane-type saponins from astragalus tmoleus var. tmoleus

2016

Five known cycloartane-type glycosides were isolated from the roots of A. tmoleus Boiss. var. tmoleus. The identification of these compounds was mainly achieved by 1D and 2D NMR spectroscopic techniques and FABMS. The results of our studies confirm that triterpene saponins with the cycloartane-type skeleton might be chemotaxonomically significant for the genus Astragalus.

Pharmacologychemistry.chemical_classificationMagnetic Resonance SpectroscopybiologyTraditional medicinePlant roots010405 organic chemistryGlycosidePlant ScienceGeneral MedicineFabaceaeAstragalus PlantSaponinsbiology.organism_classification01 natural sciencesPlant Roots0104 chemical sciences010404 medicinal & biomolecular chemistryAstragalusComplementary and alternative medicinechemistryTriterpeneGenusDrug DiscoveryAstragalus Plant
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Secondary metabolites from the roots of Paronychia chionaea

2011

Two novel secondary metabolites, compounds (1–2) were isolated from the roots of Paronychia chionaea. On the basis of spectroscopic data including 1D and 2D NMR experiments (COSY, TOCSY, HSQC, and HMBC), and mass spectroscopy, their structures were established as 6- C-[α-L-arabinopyranosyl-(1→2)-β-D-glucopyranosyl]-7- O-[β-D-glucopyranosyl]-luteolin 3′-methyl ether (1), and 2-(methoxy)-2-(3,5-dimethoxy 4-hydroxyphenyl)-ethane-1,2-diol 1- O-β-D-glucopyranoside (2).

PharmacologyMagnetic Resonance SpectroscopyStereochemistryPlant ScienceGeneral MedicineChrysoeriolmedicine.diseasePlant RootsParonychiachemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoverymedicineGlycosidesParonychiaTwo-dimensional nuclear magnetic resonance spectroscopyHeteronuclear single quantum coherence spectroscopy
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Triterpenoid saponins from the roots of two Gypsophila species.

2013

Two triterpenoid saponins with two known ones have been isolated from the roots of Gypsophila arrostii var. nebulosa, and two new ones from the roots of Gypsophila bicolor. Their structures were established by extensive NMR and mass spectroscopic techniques as 3-O-β-d-galactopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→3)]-β-d-glucuronopyranosylquillaic acid 28-O-β-d-xylopyranosyl-(1→4)-[β-d-glucopyranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-fucopyranosyl ester (1), 3-O-β-d-galactopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→3)]-β-d-glucuronopyranosylgypsogenin 28-O-β-d-xylopyranosyl-(1→4)-[β-d-glucopyranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-fuco…

Gypsophila arrostiiGypsophilaStereochemistryCell SurvivalMolecular ConformationStereoisomerismAntineoplastic AgentsCaryophyllaceaePlant ScienceHorticultureBiochemistryPlant RootsCell LineTerpeneStructure-Activity RelationshipTriterpenoidSpecies SpecificityAnimalsHumansMolecular BiologyCell ProliferationPlant rootsbiologyDose-Response Relationship DrugChemistryStereoisomerismGeneral MedicineSaponinsbiology.organism_classificationTriterpenesRatsHuman colon cancerDrug Screening Assays AntitumorTwo-dimensional nuclear magnetic resonance spectroscopyPhytochemistry
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Triterpene Glycosides from the Roots of Astragalus flavescens

2007

Six new triterpene saponins, 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (1), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (2), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-beta-D-glucopyranosyl-21-epi-kudzusapogenol A (3), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-beta-D-glucopyranosyl-21-epi-kudzusapogenol A (4), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyl-(1-->2)-beta-D-glucuronopyranosyl-22-O-alpha-L-arabinopyranosyl-21-epi-kudzus…

TurkeyStereochemistrySaponinPharmaceutical ScienceUronic acidPharmacognosyPlant RootsAnalytical Chemistrychemistry.chemical_compoundTriterpeneDrug DiscoveryTrisaccharideNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideStereoisomerismAstragalus PlantSaponinsbiology.organism_classificationTriterpenesTerpenoidAstragalusComplementary and alternative medicinechemistryMolecular MedicineJournal of Natural Products
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Chionaeosides A–D, Triterpene Saponins from Paronychia chionaea

2007

Four new triterpenoid saponins, chionaeosides A-D (1-4) were isolated from the roots of Paronychia chionaea. On the basis of their spectroscopic data, the structures of the new saponins were established as 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--3)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (1), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranoside (2), 3-O-alpha-L-arabinopyranosylgypsogenic acid 28-O-beta-D-glucopyranoside (3), and 3-O-alpha-L-arabinopyranosylgypsogenic acid (4).

TurkeyStereochemistrySaponinPharmaceutical ScienceParonychia (plant)CaryophyllaceaePharmacognosyPlant RootsAnalytical ChemistryTriterpenoidTriterpeneDrug DiscoveryTrisaccharidePharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryMolecular MedicineJournal of Natural Products
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